DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and CG18788

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_652665.3	Gene:	CG18788 / 59164	FlyBaseID:	FBgn0042126	Length:	540	Species:	Drosophila melanogaster

Alignment Length:	545	Identity:	125/545 - (22%)
Similarity:	220/545 - (40%)	Gaps:	126/545 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 KQRYIVVLLAFFGFFNVYSLRVNLSVAI------------------------------VAMTENR 70
            :||:::....|....|.|::|:.|...:                              :||..|.
  Fly    19 RQRWVLCCFTFLAIINAYTMRLCLDCTLNRIILECGGHRVDNVPQVLNPKALPNWRIELAMALNH 83

  Fly    71 TVFDADGNVSYQQDFP-----------------------------------WDSKQKGLILSSFF 100
            |.:.....:...::.|                                   |..:.:.|::.:|:
  Fly    84 TEYQLRSRLKAGKEQPDLNQISAKGTRDREPAGEKRPGQEDSQERLSCSEQWPRQTQSLVVMAFY 148

  Fly   101 YGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASH-SLEMFLFVRIIEGFFEGVTFP 164
            .||:|:...||.:..:.||..|....|.::|:||||||.|... .|...:.||::.|..||..||
  Fly   149 AGYVLSHVPGGRLAERYGGKWVLSAAILTSAVLTLLTPTAVRQGGLYALVAVRLLVGICEGPCFP 213

  Fly   165 GIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKYGWESVFYVFGTIGVIWYITWL 229
            .:.|:.|:|.|..||..:||...:|...|..:....||.|..:..|...||:.|...|.|::.:.
  Fly   214 AVCALLAQWVPEQERGMLASCVLSGGEIGITMVQLVSGLLIAEQDWPVFFYLVGGGAVAWFLGFT 278

  Fly   230 VFVKAGPELDRFCSKEECDYIQKTI-------------------GYVGS--KHVKH--------P 265
            :...:.|:...|...||.:||:...                   ||.|.  :|.:.        |
  Fly   279 LVCYSTPDHCPFIQSEEREYIRCNTSNSFLLTTGREREEMDGEDGYEGEDREHRREVEATCNTAP 343

  Fly   266 WRAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTL--------NFDLGKTGILSAVPYLAM 322
            ||::..|.|.:|::::...:.:     ..:||..|:..|        :|....|.|.:..|.:..
  Fly   344 WRSMLNSTPLWALVSTSMQQEF-----QQKLPQELQIALEEVRARGTSFSELTTIIETIAPSVGN 403

  Fly   323 GILLAVSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYLLDPTWSVVSLTIAVGLGA 387
            .|....:|.|:|.|..:.|.|.||.||..:...||..:::|:.........|||      :|:||
  Fly   404 WIASLTTGRLSDVLIEQQILTRTQTRRLMSWLVFLCGSMYMLQIKMSGARIWSV------LGMGA 462

  Fly   388 FAWSGFAVNHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLV 452
            : ::...:..||::|.:|..||||......:|.::.|.|      .|...:::::..:.|.::::
  Fly   463 Y-YASIKLLPLDMSPNYAGTLMGISGGMGALPALLMPYL------EQLETDYKLVSSVRAAMWVI 520

  Fly   453 GCVIYWFYCSGDLQEWAKTPEQKAQ 477
            |.    .|.|||:|.: ..||::.|
  Fly   521 GA----SYISGDVQAF-NQPEREPQ 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	123/541 (23%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	115/520 (22%)
CG18788	NP_652665.3	MFS	129..>280	CDD:119392	47/150 (31%)
CG18788	NP_652665.3	MFS_1	135..498	CDD:284993	100/374 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.970