DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and NaPi-T

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001260981.1	Gene:	NaPi-T / 36651	FlyBaseID:	FBgn0016684	Length:	524	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	139/499 - (27%)
Similarity:	242/499 - (48%)	Gaps:	55/499 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RYIVVLLAFFGFFNVYSLRVNLSVAIV-------AMTENRTVFDAD------------------- 76
            |.::..:.|.||...|.:|:||::.||       |:|.|.|..::.
  Fly     7 RTVLWYMTFIGFIVNYMIRINLNITIVDMIAGKGAITSNETHENSTDLAALAEMNERFSLERWFL 71

  Fly    77 --GNVSYQQD-FPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTP 138
              .|:.|::: |.|:.||:|.:|.|||:.:...|..||.:.||.|..:|||...|.......|.|
  Fly    72 DWANIPYEKNGFHWNEKQQGALLGSFFWAHWTLQIPGGILATKYGTKLVFGWSNGIGVFCCFLIP 136

  Fly   139 MAASHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGF 203
            :.:..|....:.:|:.:|:..|:.:|.:|.:.|:|.||.|||:..| |:.|:..|..:..|..|:
  Fly   137 IVSYWSYTGLIILRVFQGWITGLAWPSMHVLTAKWIPPNERSKFVS-AYLGSSVGVALFYPIFGY 200

  Fly   204 LATKYGWESVFYVFGTIGVIWYITWLVFVKAGPELDRFCSKEECDYIQKTIG--YVGSKHVKHPW 266
            :.....||.|:|:.|.:|.:|:|.|...|...|......:..|..:|:|::|  ..|||. ..||
  Fly   201 IIDWTRWEWVYYICGIVGTLWFIAWQFLVFDSPAEHPRIADSERKFIEKSLGASIQGSKG-PTPW 264

  Fly   267 RAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGY 331
            :||.||.|.:..:.:.:...||.:||:|..|::.|...::::..||.||.:|:|...:...|...
  Fly   265 KAIATSRPVWLNVVAQWGGIWGLFTLMTHAPTYFRLIHHWNIRATGFLSGLPHLMRMLFAYVFSI 329

  Fly   332 LADWLQVKGIWTTTQVRR--NFNCGAFLAQTVFMMLTAYL-LDPTWSVVSLTIAVGLGAFAWSGF 393
            .||:|......:.|.||:  .|.|..  .:.:.::..||. .:.|.::|.:|:|..|.....||.
  Fly   330 FADYLLRTDKMSRTNVRKLATFICCG--TKGLIVLALAYFGYNATAAIVLVTVATMLHGAVSSGP 392

  Fly   394 AVNHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVV-TNQTSDEWRIIFFISAGIYLVGC-VI 456
            ..:.:|::|.:|.:::|:......:||.:||.:.|.:. .|||.|.|:.:|.::: :.|.|. ::
  Fly   393 LASMVDLSPNYAGIVLGVSGMIGGMPGFISPFIVGQLTHNNQTIDAWKNVFLLTS-LMLTGSGIL 456

  Fly   457 YWFYCSGDLQEW----AKTPEQKAQE----------AEEKAQLQ 486
            |..:....||.|    .:.|:...:|          .|||..|:
  Fly   457 YVLFSESKLQPWNSGCHQLPDSGLKELQNLGRDQDDEEEKKPLK 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	134/478 (28%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	129/453 (28%)
NaPi-T	NP_001260981.1	2A0114euk	1..474	CDD:129972	133/471 (28%)
NaPi-T	NP_001260981.1	MFS	76..460	CDD:119392	115/388 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970