DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS9 and Slc17a5

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001009713.1	Gene:	Slc17a5 / 363103	RGDID:	1311388	Length:	495	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	189/448 - (42%)
Similarity:	284/448 - (63%)	Gaps:	16/448 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 RYIVVLLAFFGFFNVYSLRVNLSVAIVAM-------TENRT-----VFDADGNVSYQ---QDFPW 87
            ||.:.||||.|||.:|:||||||||:|.|       |:|||     ...|...|.:.   :.:.|
  Rat    39 RYNLALLAFCGFFVLYALRVNLSVALVDMVDSNSTLTDNRTSKECAEHSAPVKVHHNHTGKKYQW 103

  Fly    88 DSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASHSLEMFLFVR 152
            |::.:|.||.|||||||:||..|||:.::|||.::.|.||..||:.||.||:||...:...:.:|
  Rat   104 DAETQGWILGSFFYGYIVTQIPGGYMASRIGGKLLLGLGILGTAVFTLFTPLAADLGVVALIVLR 168

  Fly   153 IIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKYGWESVFYVF 217
            .:||..||||||.:||:|:.|:||||||::.:|::||...|||:::|.||.:.....|..|||:|
  Rat   169 ALEGLGEGVTFPAMHAMWSSWAPPLERSKLLTISYAGAQLGTVISLPLSGIICYYMNWTYVFYLF 233

  Fly   218 GTIGVIWYITWLVFVKAGPELDRFCSKEECDYIQKTIGYVGSKHVKHPWRAIFTSMPFYAIMASH 282
            |.:|::|:|.|:..|...||..:..|..|.:||..::....|.....||.:|..|:|.:||:.:|
  Rat   234 GLVGIVWFILWMWIVSDTPETHKTISHYEKEYIVSSLKNQLSSQKVVPWVSILKSLPLWAIVVAH 298

  Fly   283 FSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQV 347
            ||.||.||||||.||:::::.|.|::.:.|.|||:||....:.:.|.|..||:|:||..::|..|
  Rat   299 FSYNWTFYTLLTLLPTYMKEILRFNVQENGFLSALPYFGCWLCMIVCGQAADYLRVKWNFSTISV 363

  Fly   348 RRNFNCGAFLAQTVFMMLTAYL-LDPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLMGI 411
            ||.|:....:...||::...:: .|.:.:|..|||:..||.||.|||::|||||||.:|.:|:||
  Rat   364 RRIFSLIGMVGPAVFLVAAGFIGCDYSLAVAFLTISTTLGGFASSGFSINHLDIAPSYAGILLGI 428

  Fly   412 GNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWA 469
            .||||||||::.|::...:..:.|..||:.:|.|:|.|.:.|.:.:..:..|::|.||
  Rat   429 TNTFATIPGMIGPIIAKSLTPDNTIKEWQTVFCIAAAINVFGAIFFTLFAKGEVQNWA 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	189/448 (42%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	183/433 (42%)
Slc17a5	NP_001009713.1	2A0114euk	30..491	CDD:129972	189/448 (42%)
Slc17a5	NP_001009713.1	MFS	99..478	CDD:119392	159/378 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	1	1.100	-	-	O	PTHR11662
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X201
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.810