DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS9 and Slc17a4

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_795990.2	Gene:	Slc17a4 / 319848	MGIID:	2442850	Length:	492	Species:	Mus musculus

Alignment Length:	456	Identity:	133/456 - (29%)
Similarity:	232/456 - (50%)	Gaps:	46/456 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 FNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQ------QD-------------FPWDSKQKGLI 95
            |::|:.::|||.||.||. |.||..:..|.|.:      ||             :.|..:.:|::
Mouse    45 FSIYTQQMNLSFAITAMV-NTTVASSQLNASTERPPTNSQDVWNETLQESKAPVYDWTPEIQGIL 108

  Fly    96 LSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASHSLEMFLFVRIIEGFFEG 160
            |||..||..:.....||:....|...|.|.|:..:::|||..|:||...:.:.:.:|:|:|..:.
Mouse   109 LSSLSYGSFIAPIPTGYVAGVFGAKYVVGLGLLISSVLTLFIPLAADAGVALLIVLRVIQGMAQV 173

  Fly   161 VTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKYGWESVFYVFGTIGVIWY 225
            :...|.:::||:|:||.|||::.:||.:|:..||.:.:...|.:....||..:||:||.||....
Mouse   174 MVLTGQYSLWAKWAPPQERSQLITIAASGSMLGTFLVLIAGGLICQALGWPYIFYIFGGIGCACC 238

  Fly   226 ITWLVFVKAGPELDRFCSKEE-----CDYIQK--TIGYVGSKHVKHPWRAIFTSMPFYAIMASHF 283
            :.|...|...|:...|.|..|     |...|:  ::|:      ..|.:|:..|:|.:||:.|:|
Mouse   239 LLWFPLVYDDPQNHPFISTGERRYITCSLAQEDCSLGW------SLPIKAMVKSLPLWAIVVSYF 297

  Fly   284 SENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVR 348
            .|.|...|::...|:::...|..:|..:|||||:|::...:.:.:.|.|||:|..:.|.....:|
Mouse   298 CEYWLLSTVMAYTPTYISSVLQANLRDSGILSALPFMFGCVCIILGGLLADFLLSRKILRLVTIR 362

  Fly   349 RNFNCGAFLAQTVFMMLTAYLLDPTW-------SVVSLTIAVGLGAFAWSGFAVNHLDIAPQHAS 406
            :.|.....||.      :..||...|       ::..|.::....:...||..:|.|||||::|.
Mouse   363 KLFTAVGVLAS------SGILLPLPWVRSSRSTTMAFLVLSSVFASLCDSGALINFLDIAPRYAG 421

  Fly   407 VLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWAKT 471
            .|.|:...|:.:.|.::|.:.|:.::..:...||.:||::|.|.:||.:.|..:...::|:|||.
Mouse   422 FLKGLLQVFSYLAGGIAPTVAGFFISQDSEFGWRNVFFLAAAIDVVGLLFYLIFSRAEVQDWAKE 486

  Fly   472 P 472
            |
Mouse   487 P 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	133/456 (29%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	128/442 (29%)
Slc17a4	NP_795990.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
		2A0114euk	27..486	CDD:129972	131/453 (29%)
		MFS	98..475	CDD:119392	112/388 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810