DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and SPAC1002.16c

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_593504.1	Gene:	SPAC1002.16c / 2543262	PomBaseID:	SPAC1002.16c	Length:	499	Species:	Schizosaccharomyces pombe

Alignment Length:	530	Identity:	114/530 - (21%)
Similarity:	193/530 - (36%)	Gaps:	124/530 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 NNEITESE--PLTWRFWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQ 82
            |..:|:||  .|.:|........:::|....|.:    |.|:..|.||
pombe    40 NTHLTKSERDSLLFRLDLVLAPTIMILYLVAFLD----RSNIGNAKVA----------------- 83

  Fly    83 QDFPWDSKQKG----LILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASH 143
             ..|.|.|.||    :|.|.|:..:||.:.....:..|:....:....:.|.::.|:.|...  |
pombe    84 -GLPEDLKLKGDQFNIIASVFYVTFILFEMPTTLLMKKVQPKRMLAFIVISYSLTTIFTGFC--H 145

  Fly   144 SLEMFLFVRIIEGFFEGVTFP----GIHAVWAR--WSPP---LERSRMASIAFAGNYAGTVVAMP 199
            :....|..|::.||.|...||    .:..:::|  .:|.   |..|...|.||.|.:|..|:.|.
pombe   146 NFGGLLAARLVLGFCEAGLFPCLALYLTMIYSRVELAPRIAYLFASSALSGAFGGLFAYAVLHMD 210

  Fly   200 CSGFLATKYGWESVFYVFGTIG-----VIWYITWLVFVKAGPELDRFCSKEECDYIQK-TIGYVG 258
            ..|..|   ||..:|.:.|.||     .:::|......||.     |.||...:.::| .:....
pombe   211 GVGGFA---GWRWLFIIEGLIGFVCGVAVYFIIPNDITKAW-----FLSKTHQEMMRKRQLERAA 267

  Fly   259 SKHVKH-PWRAI---FTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDLGKTG------- 312
            .....| .|:.:   ||....|....|.|.::...|...|.||:.:.     .:|.|.
pombe   268 DLEAAHFDWKGVKSAFTDFKVYLYALSEFGQDTCLYGFSTFLPAIIS-----GMGYTSLSVQYMT 327

  Fly   313 ----ILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYLL--- 370
                ||.|..|:|       :.:|:|....:||             ..:...:|.::...||
pombe   328 IPVYILGAATYIA-------ASFLSDRFHHRGI-------------ILIIGNIFPIVGYILLLAC 372

  Fly   371 DPTWSVVSLTIAV-GLGAFAWSGFAVNHL--DIAPQH-----ASVLMGIGNTFATIPGIVSPLLT 427
            ....||:.....: .:|.:..:|..|..|  :|||.:     .|:.:.|.|:...:.|.:.....
pombe   373 QNNKSVLYFACYLCSVGVYTGAGLNVTWLSANIAPHYKRATAISLQLAIANSSGILAGQIYRYPP 437

  Fly   428 GYVVTNQTSDEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWAKTPEQKAQEAEEKAQLQLTQTAG 492
            .|:..:.||   .|..|||..:::|.  |::.               |.|.::::..|..:.|..
pombe   438 KYIAGHLTS---LIAIFISTVLHVVN--IFFL---------------KHQNSKKQKSLASSSTID 482

  Fly   493 FVNSGAELKD 502
            ......:.||
pombe   483 LSEQPKDDKD 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	103/483 (21%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	102/462 (22%)
SPAC1002.16c	NP_593504.1	MFS	63..455	CDD:119392	100/451 (22%)
SPAC1002.16c	NP_593504.1	2A0114	65..435	CDD:273326	93/426 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050