DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and vht1

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_594801.1	Gene:	vht1 / 2542518	PomBaseID:	SPAC1B3.16c	Length:	568	Species:	Schizosaccharomyces pombe

Alignment Length:	461	Identity:	82/461 - (17%)
Similarity:	159/461 - (34%)	Gaps:	125/461 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 FFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQDFPWDSKQKGLILSSFFYGYILTQFLGGYI 113
            :|....||..:|::.       |:..|.|:...|....:.:....|.|:.|:.|||:.:
pombe    93 YFLSCCLRFTVSLSF-------TMNTAQGHSLIQTLSGYSAHYLALGLALFYVGYIIFE------ 144

  Fly   114 GTKIGGNIVFG---TGIGSTAILTLLTPMAASHSL--------EMFLFVRIIEGFFEGVTFPGIH 167
               :..|::..   ..|..:.|...:..:.|.|::        :.::.:|...|..|...:||:.
pombe   145 ---VPSNLMMAFIEPRIWVSRIQLTIGVVGACHAVLGTKHGNAQSYVALRFFLGVAESGLWPGLA 206

  Fly   168 AVWARW--SPPLERSRMASIAFAGNYAGTVVAMPCSGFLATK-----YGWESVFYVFGTIGVIWY 225
            ...:||  ...|.: |:.....|...|...|::..:||....     ||::.:|.::|.:.:...
pombe   207 YYMSRWYRGKHLGK-RIGWYYTAAQIAAAAVSLVSAGFQKMDGARGLYGYQWMFLIWGVVAIAQA 270

  Fly   226 IT---WLVFVKAGPELDRFCSKEECDYIQKTIGYVGSKHVKHPWRAIFTSMPFYAIMASHFSE-- 285
            ::   ||..|         .|||....:...|..........|.|..|.:....::.:.:.:|
pombe   271 LSIPWWLPAV---------ASKEHRKSLSSFIPLPKWMKTLSPQRIGFLTPADKSLHSRYIAEMN 326

  Fly   286 ---NWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAM--GILLAVSGYLADWLQVKGIWTTT 345
               .|       |....|:..|:        |...|::.|  ||:...:|.
pombe   327 VGKRW-------QWSDLLKSCLD--------LRVWPFILMYFGIVGVGNGI-------------- 362

  Fly   346 QVRRNFN-CGAFLAQTVFMMLTAYLLDPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLM 409
                 || |...:.:          ::|::|.:.:::   |.|..|...|:..:.:.|.:..
pombe   363 -----FNYCTLIIEE----------INPSFSGIDISL---LNAPIWLADALGIVTVMPLYDR--- 406

  Fly   410 GIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVG---------CVIYWFYCSGDL 465
             ....|:...|....::.|..|.|.....|...    .|:.::|         |:.   :||..:
pombe   407 -FHKKFSFFTGSCLIIIAGLAVANYAPRAWSRY----GGLLMIGFGLGPTVPICMA---WCSASM 463

  Fly   466 QEWAKT 471
               |||
pombe   464 ---AKT 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	82/461 (18%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	77/448 (17%)
vht1	NP_594801.1	HpaX	80..503	CDD:131385	82/461 (18%)
vht1	NP_594801.1	MFS	94..493	CDD:119392	82/460 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000