DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and SPBPB10D8.01

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_595045.1	Gene:	SPBPB10D8.01 / 2541399	PomBaseID:	SPBPB10D8.01	Length:	552	Species:	Schizosaccharomyces pombe

Alignment Length:	578	Identity:	108/578 - (18%)
Similarity:	195/578 - (33%)	Gaps:	180/578 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LEQVHQNNNEITESEPLTWRFWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADG 77
            |::......|..:.||||.:..::.|:                ::..:|.::.|..:..::....
pombe    57 LDETFSFMQEAKDLEPLTPKQDKRLRW----------------KLYFTVLVMLMILDMMLYIDKA 105

  Fly    78 NVSYQ------QDFPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLL 136
            .:||.      :|...:|.|...|.:.|:.|:::.|..|..:..:..   |......|||:.|::
pombe   106 TLSYSSILGLFEDTHINSNQYNDINTLFYVGFVIGQIPGHMLLQRFP---VSKFVAASTALWTII 167

  Fly   137 TPM-AASHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPC 200
            ..: .|:::....:.:|...|..|....|.:.|....:.|..|::.:....:...|...:.|
pombe   168 IFLHCAAYNFSGLMALRFFLGLVESSLLPTMEATIGMFFPHSEQALLQPFFYISCYGCNIPA--- 229

  Fly   201 SGFLATKYG----------WESVFYVFG------TIGVIWYITWLVFVKAGPE---LDRFCSKEE 246
             ||:|  ||          |:....:.|      |||:.:|.         |:   ..||.:|:|
pombe   230 -GFIA--YGVQYAKNTISPWKLFMIIVGGITFFLTIGLFFYY---------PDNTSTARFLTKKE 282

  Fly   247 CDYIQKTIGYV-GSKH----------------VKHPWRAIFTSMPFYAIMASHFSENWGFYTLLT 294
            ..|   |:..| .|.|                :|.|...:||    :.:..:..|.|      |.
pombe   283 RLY---TVDRVRRSNHSGIESKTFKKYQVIEALKDPVTWLFT----FHVFCNQLSNN------LA 334

  Fly   295 QLPSFLRDTLNF-DLGKT--GILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVRRNFNCGAF 356
            ...:.|..:||. ||..|  |:.||             ||                    ||.:.
pombe   335 YQQNLLFTSLNVSDLNSTLVGVASA-------------GY--------------------NCVSA 366

  Fly   357 LAQTVFMML---TAYLLDPTWSVVSLTIAVGLGAFAW-------------SGFAVNHLDIAPQHA 405
            :..|..|.:   .:......|.:.|:...:...|.:|             |.|.:
pombe   367 IIATYMMSVIKNQSAFHGAIWYIPSIAGGIACVAMSWDHKIGELAAIIIASNFGI---------- 421

  Fly   406 SVLMGIGNTFATIPGIVSPL------LTGYVVTN-------QTSD------EWRIIFFISAGIY- 450
            ..::.:|.|.|:..|....|      :.||.:.|       |:.|      .|.:...|:..:.
pombe   422 PFIISLGWTTASCAGYTKKLTRGVMFMIGYAIANIIGPQMWQSRDAPRYYPAWIVQIVIAWSVSP 486

  Fly   451 LVGCVIYWFYCSGDLQEWAKTPEQKAQEAEEKAQLQLTQTAG------FVNSGAELKD 502
            .|..:|.|.....:.:..|...:.|  |..||..::...::|      :.||..:|.|
pombe   487 FVLLIIRWILVRRNKKRLALLEQNK--EQYEKTWIETIDSSGNHVSGFYENSMLDLTD 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	94/520 (18%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	91/499 (18%)
SPBPB10D8.01	NP_595045.1	MFS	90..492	CDD:119392	88/475 (19%)
SPBPB10D8.01	NP_595045.1	2A0114	101..497	CDD:273326	89/469 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050