DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS9 and SPBC1683.12

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_595068.1	Gene:	SPBC1683.12 / 2539910	PomBaseID:	SPBC1683.12	Length:	482	Species:	Schizosaccharomyces pombe

Alignment Length:	496	Identity:	108/496 - (21%)
Similarity:	190/496 - (38%)	Gaps:	110/496 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 LLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQDFPWDSKQKGLILSSFFYGYILTQ 107
            :|.|..|.:    |.|:..|.|              |..::|....:.|....:|.|:..||..:
pombe    50 VLYFLSFLD----RANIGNAAV--------------VGLKEDLKLQAYQYSAAVSVFYATYITAE 96

  Fly   108 FLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASH-SLEMFLFVRIIEGFFEGVTFPGIHA-VW 170
            .....:..|.|.:......|...:::|:.|.....: ||   :..|::.|..||..||.:.. :.
pombe    97 TPSVLLVKKFGPHYYLSAMIIGWSLVTIFTCFVRHYWSL---VLTRLLLGICEGGFFPCLSLYIS 158

  Fly   171 ARWSPPLERSRMASI----AFAGNYAGTVVA----MPCSGFLATKYGWESVFYVFGTIGVIWYIT 227
            ..:....:..|:|.:    .|:|.:.|.:..    :|.|..| ..:||  ::.:.|.|..|..:
pombe   159 MTYKREEQGKRLAYLYVCSCFSGAFGGLIATGLTKIPKSSGL-PNWGW--LYIIEGLISAISAL- 219

  Fly   228 WLVF-VKAGPELDRFCSKEECDYI-------QKTIGYVGSKHVKHPW---RAIFTSMPFYAIMAS 281
            |::| :...|...||.:..|.:.:       ||   |:||.:  ..|   |..|.....|.....
pombe   220 WILFCLPDDPSTARFLNPREKELMKIRAEQRQK---YMGSPN--FDWTQFRKAFKDPKMYMSCVI 279

  Fly   282 HFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILS---AVPYLAM-GILLAVSGYLADWLQVKGIW 342
            .|.::...|.:.|.|||.|:    .:||.:.:.:   :||..|: ||.:.|...|:|...::| |
pombe   280 QFCQDLVLYGISTFLPSILK----LELGYSSLAAQYMSVPVYALGGISVYVICLLSDRTNIRG-W 339

  Fly   343 TTTQVRRNFNCGA-FLAQTVFMMLTA-----------YLLD-PTWSVVSLTIAVGLGAFAWSGFA 394
                    |..|. |.....|::|.|           ||:. |.:..|:|.|       .|
pombe   340 --------FIIGMNFFGLAGFIILLATTNSAANYVATYLIALPLYPTVALNI-------TW---- 385

  Fly   395 VNHLDIAPQH-ASVLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVG---CV 455
            :|: ::||.: .:..:|...|...:.|:::    |.|   ..|..:::....:.|..:||   ..
pombe   386 INN-NMAPHYRRATALGCNQTIGNLAGVIA----GQV---YRSSPYKLGHGFALGCTVVGTLTAT 442

  Fly   456 IYWFYCSGDLQEWAKTPEQ--KAQEAEEKAQLQLTQTAGFV 494
            ...||    ||...|..::  ..:..:||.:........||
pombe   443 AMRFY----LQRQNKIKQEILNGERVDEKKERDGCDALDFV 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	104/477 (22%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	99/458 (22%)
SPBC1683.12	NP_595068.1	MFS	47..417	CDD:119392	94/425 (22%)
SPBC1683.12	NP_595068.1	2A0114	50..417	CDD:273326	94/425 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I2672
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	69	1.000	Inparanoid score	I1933
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050