DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS9 and MFS1

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_726254.1	Gene:	MFS1 / 246519	FlyBaseID:	FBgn0050272	Length:	497	Species:	Drosophila melanogaster

Alignment Length:	490	Identity:	162/490 - (33%)
Similarity:	264/490 - (53%)	Gaps:	43/490 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 QRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQDFPWDSKQKGLILSSFFY 101
            ||::...|.|......|..:.|..||:||||      :|:.......::.|:..::..||||||:
  Fly    13 QRHLQTFLLFLSIVVNYMAKFNAGVAVVAMT------NAENTNPNFPEYDWNEMERSYILSSFFW 71

  Fly   102 GYILTQFLGGYIGTKIGGNI-VFGTGIGSTAILTLLTPMAAS-HSLEMFLFVRIIEGFFEGVTFP 164
            |||||||:||::..:.|..| :|.:.||| |:|.:|.|...| ...:.:..:|:..|.|:|..||
  Fly    72 GYILTQFMGGWLCRRYGARITMFVSTIGS-ALLVVLIPWCVSWGGWQAYCAIRMSMGLFQGFLFP 135

  Fly   165 GIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFL-ATKYGWESVFYVFGTIGVIWYITW 228
            .|||..|.|.|..||:|:.::|..|...||:|||..||.| |:..||..:|||...:||:|.|.|
  Fly   136 CIHAHLANWCPVKERNRLGALANTGIDCGTLVAMFASGLLAASSIGWPGIFYVSCGVGVLWCIVW 200

  Fly   229 LVFVKAGPELDRFCSKEECDYIQKTIGYVGSKHVKH-----------PWRAIFTSMPFYAIMASH 282
            .:|....|...:|..:.|.:||:.:|.  .|:..:.           ||:||:||:||:|:|.:.
  Fly   201 WIFGANQPRESKFIGEAELNYIETSIN--SSRKAEEAELKATGPIPVPWKAIWTSVPFWALMVTR 263

  Fly   283 FSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQV 347
            ..::||:.||.|::|:::...|..|:....:.||:|||...::..|...:||.|..:||.:.|.:
  Fly   264 CCQSWGYSTLQTEMPAYMNGVLLMDMKSNALYSALPYLTSWVMAFVYLIIADILLTRGIMSITGI 328

  Fly   348 RRNFNCGAFLAQTVFMMLTAYL--LDPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLMG 410
            |::.|..||......::..::|  ...|.:||.:...||:.|.:..|..:|.:|::|.||.:|||
  Fly   329 RKSVNSIAFFVPAAALIGVSFLDNTQKTLAVVLMCANVGINAGSTIGSTINTIDLSPNHAGILMG 393

  Fly   411 IGNTFATIPGIVSPLLTGYVV-TNQTSDEWRIIFFISAGIYLVGCVIYWFY-------------- 460
            |.||.:.|..|::|||.|.:| .:...::|:|:|.|||.|:.||.::|..:
  Fly   394 IVNTASNIVPILTPLLVGIIVKDDHDREQWQIVFIISAVIFCVGNIVYVAFGKMVNQPWDAPDFM 458

  Fly   461 ---CSGDLQEWAKTPEQKAQEAEEKAQLQLTQTAG 492
               .|.:|||...:...:||.:|:..:.:..::.|
  Fly   459 DKQRSSNLQEVGHSKALEAQGSEKVEEAKRNESEG 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	157/472 (33%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	152/434 (35%)
MFS1	NP_726254.1	MFS	18..444	CDD:119392	152/434 (35%)
MFS1	NP_726254.1	2A0114euk	19..456	CDD:129972	152/445 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	116	1.000	Domainoid score	I288
eggNOG	1	0.900	-	-		E1_KOG2532
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	134	1.000	Inparanoid score	I245
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	1	1.000	-	-		mtm14983
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11662
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.970