DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and C01B4.8

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_503682.1	Gene:	C01B4.8 / 182055	WormBaseID:	WBGene00015272	Length:	478	Species:	Caenorhabditis elegans

Alignment Length:	515	Identity:	123/515 - (23%)
Similarity:	227/515 - (44%)	Gaps:	89/515 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 EQVHQNNNEITESEPLTWRF--WRKQRYIVVLLAF--FGFFNVYSLRVNLSVAIVAMTENRTVFD 74
            |:..:.::|::|:...|.:.  ....||::::|..  .....:.||..|.:|  :.|::   |.|
Worm     8 EEKIEKSDEMSENSRKTSKILCCNLTRYLILILTLTCLTLLQMNSLAFNFTV--ICMSD---VSD 67

  Fly    75 ADGNVSYQQDFPW--DSKQKGLILSSFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAIL-TLL 136
             |.::::..:..|  ||..|.|:.||...|.:|...:...:..::|..:|... .|..:|| |:|
Worm    68 -DYHITHPNETHWFEDSNMKSLVFSSMAVGGLLGLLIAMPLMHRVGVRLVLSI-CGVFSILGTIL 130

  Fly   137 TPMAASHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCS 201
            .|:|...:....|.||.::|....:.|..:.:|...|:|..|.....::.........|:.||.|
Worm   131 FPLAVEWNFFSVLVVRFLQGLGISMVFTVLGSVPTAWAPNNESGTFLAVLSCAFQWSNVICMPIS 195

  Fly   202 GFLA-TKYGWESVFYVFGTIGVIWYITWLVFVKAGPELDRFCSKEECDYIQKTIGYVGSKHVKH- 264
            |||. :.:||.|::|:||.:.:::::.:..|....|...|..|.:|...|      :..|.|.|
Worm   196 GFLCESSWGWRSIYYLFGIVTIVFFLAFYFFYTDSPTDHRNVSNKELSLI------LQDKTVTHK 254

  Fly   265 ---PWRAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILL 326
               |:.||...........|:...|.||.||:...|::||:.|||::..||..||:|:|....:.
Worm   255 EPVPYLAICKDPCVLVTWMSNIGGNLGFLTLVLYGPTYLREVLNFEVRGTGFASALPFLLSAAVK 319

  Fly   327 AVSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYLLDPTWSVVSLTIAVG-LG---- 386
            :::|.|:|    :..:.:.:||... ||.                    |..|.:|:| :|
Worm   320 SIAGQLSD----RCDFVSERVRFTI-CGI--------------------VARLGLAIGYIGMATT 359

  Fly   387 --------AFAWSGFAVNHLDI----------APQHASVLMGIGNTFATIPGIVSPLLTGYVVTN 433
                    ||.:| .||:.|:|          ..||....:.:....|.:....:|:|.|.:..:
Worm   360 SSRLVAQIAFTFS-IAVSGLNIMGTVKCLQLRCKQHVHFAVSVIALMAYVIQFGAPILVGIICPD 423

  Fly   434 QTSDEWRIIFFISAGIYLVGCVIY-------WFYCSGDLQEWAKTPEQKAQEAEEKAQLQ 486
            .|:::|...|.|      ||.:::       || .:.:..::..:.|::.:.|:.| :||
Worm   424 NTAEQWGWFFLI------VGIIVFVTSAPFPWF-TTAEPADYTLSREKQLEIAKHK-ELQ 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	115/478 (24%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	111/457 (24%)
C01B4.8	NP_503682.1	MFS	56..443	CDD:391944	107/431 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820