DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and slc-17.8

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001023848.1	Gene:	slc-17.8 / 179234	WormBaseID:	WBGene00017798	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	491	Identity:	135/491 - (27%)
Similarity:	237/491 - (48%)	Gaps:	27/491 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 KHLEQVHQNNNEI-TESEPLTWRFWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFD 74
            :.:..||..::.| ::..|||:|::...|::..::..|.|..|:.:..|:.:|||.|..:...:|
Worm    25 RSMSSVHPISDGIPSQQRPLTYRWFPSWRFMTSIMLCFCFGCVHLMNSNMGMAIVCMVNSSATYD 89

  Fly    75 ADGNVSYQQD----FPWDSKQKGLILSSFFYGYILTQFLGGYIGTKIGGN--IVFGTGIGSTAIL 133
               |.:|.::    ..|.|.::|.|.|:|..|.::..|.|| :..|....  |:....|.|.|..
Worm    90 ---NETYPENAAPLLDWSSDEQGYIFSAFNAGLLVMLFTGG-MADKFNAKYMILVSVAIASLANF 150

  Fly   134 TLLTPMAASHSLEMFLFVRIIEGFFEGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAM 198
            ||  |..|..|:...:|.|.:.||.:.:..|.::::..||.|..|||....:|..|...||::.:
Worm   151 TL--PWMAPISVYWAIFSRFLVGFADALLQPAMNSLITRWFPTSERSYALGLATGGRQIGTLIII 213

  Fly   199 PCSGFLATKY----GWESVFYVFGTIGVIWYITWLVFVKAGPELDRFCSKEECDYIQKTIGY--- 256
            |.:|.|.::.    ||.|:||:.|.|||::..:::......|......|..|..:|  ||..
Worm   214 PAAGALCSQTEIFGGWPSIFYLSGFIGVLFIFSYIFLGADKPSKQSCISDNELKFI--TISNQSE 276

  Fly   257 -VGSKHV--KHPWRAIFTSMPFYAIMASHFSENWGFYTLLTQLPSFLRDTLNFDLGKTGILSAVP 318
             ||.|..  |.||:.|..|...:|.:.|.....:...||:..|||:|.|..::...:.|||||:|
Worm   277 DVGKKRTERKVPWKNILKSGAVWASVISLVCHEFPLMTLIMFLPSYLHDVHHYHSTENGILSALP 341

  Fly   319 YLAMGILLAVSGYLADWLQVKGIWTTTQVRRNFNCGAFLAQTVFMMLTAYL-LDPTW-SVVSLTI 381
            .:::......|.||..|||....|....:.:..|....:...||::...:| .:..| :|:.|.:
Worm   342 TVSLWFAKIGSSYLNTWLQKNTTWKKDTICKVLNSIGSIGLGVFLLAATFLDNEHAWMAVLFLCL 406

  Fly   382 AVGLGAFAWSGFAVNHLDIAPQHASVLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFIS 446
            ::........|..:..:.:||.::..:.|....|..:.||:.|::|..:|.::|:.||.::|:||
Worm   407 SMASAGLHTPGCQLALVSVAPAYSGAVTGFTFFFVAVSGIIHPIITKMIVKDRTAAEWNLVFYIS 471

  Fly   447 AGIYLVGCVIYWFYCSGDLQEWAKTPEQKAQEAEEK 482
            ..|.:...:|:..:.|.::|.|||:.....||...|
Worm   472 TVIAIFPIIIFNVWGSTEVQWWAKSKASMQQEPNNK 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	125/456 (27%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	119/435 (27%)
slc-17.8	NP_001023848.1	MFS_SLC17	57..486	CDD:340876	119/436 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28615
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.930