DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MFS9 and T27D12.1

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001254320.1	Gene:	T27D12.1 / 174820	WormBaseID:	WBGene00012085	Length:	502	Species:	Caenorhabditis elegans

Alignment Length:	475	Identity:	110/475 - (23%)
Similarity:	204/475 - (42%)	Gaps:	34/475 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 FWRKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQDFPWDSKQKGLILS 97
            |..:.|:::::|......:::|..:..:.|:|.|.::.:...|..|.:.::.. :.|.|..|.::
Worm    29 FGTRTRFVIMVLILLCLTSIWSNILAFNFAVVCMDDDDSEMGASLNGTARKTH-FTSTQNSLAMA 92

  Fly    98 SFFYGYILTQF----LGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASHSLEMFLFVRIIEGFF 158
            ......:|..|    |.|.:|.:   .:..|.||.| |:.|||.|::.......||.||.::||.
Worm    93 IVAIAALLGNFPIVQLVGMVGIR---TVFAGLGILS-AVSTLLIPLSIRMGFYYFLAVRFLQGFA 153

  Fly   159 EGVTFPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKYGWESVFYVFGTIGVI 223
            ....||.|.:..|:||...:.....|...|.......:.||.||.|.:.:.|.|:||..|.:.::
Worm   154 FAANFPVIGSFCAKWSYFKQNGLFVSSLVAYVQLSPAITMPASGALCSAFKWPSIFYAHGAVSLL 218

  Fly   224 WYITWLVFVKAGPELDRFCSKEECDYIQKTIGYVGS--KHV--KHPWRAIFTSMPFYAIMASHFS 284
            .::|:.:|.:..|:...|....|...|  :||.:.:  |..  |.|:..|..:...:|:..:..
Worm   219 LFVTYALFYRNSPQKHPFVGNVELKKI--SIGKIAAVDKRALKKVPYGPILKTPAIWAVWVAAI- 280

  Fly   285 ENWGFYTLLTQL----PSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQV--KGIWT 343
               |.:|.:..:    |.:|...|.|.:..|||.:|:|.........:.|..:|.|..  :|:
Worm   281 ---GNFTCVNMMFLFSPIYLSKVLGFPVHSTGITAAIPPFLQFSSKLICGAASDRLTCLSEGV-- 340

  Fly   344 TTQVRRNFNCGAFLAQTVFMMLTAYLLDP---TWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHA 405
               ..|.||..||:....|:.:.|::.|.   ...:|....|..|||.....|....: ::.|::
Worm   341 ---KFRLFNTLAFVGSAGFLCVLAFMGDEHKRNNMIVLGCAAAMLGATTGGFFKAGPV-LSKQYS 401

  Fly   406 SVLMGIGNTFATIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWAK 470
            ..:.|..:...||..::.|.....:..|.|.:||:.:|.|:..:.::..:.:..:..||..||..
Worm   402 HFVTGNISLGITITMLIVPFFVNALTPNNTQEEWKYVFLITGAVMVITNIFFVIFVRGDPCEWTS 466

  Fly   471 TPEQKAQEAEEKAQLQLTQT 490
            ....:|....:..|..:..|
Worm   467 DSFHRASSVADFEQHHIRNT 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	106/455 (23%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	101/434 (23%)
T27D12.1	NP_001254320.1	MFS	56..456	CDD:391944	99/416 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D497052at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920