DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment MFS9 and slc17a6b

DIOPT Version :9

Sequence 1:	NP_650889.1	Gene:	MFS9 / 42426	FlyBaseID:	FBgn0038799	Length:	502	Species:	Drosophila melanogaster
Sequence 2:	NP_001122293.1	Gene:	slc17a6b / 100149756	ZFINID:	ZDB-GENE-030616-554	Length:	584	Species:	Danio rerio

Alignment Length:	548	Identity:	208/548 - (37%)
Similarity:	311/548 - (56%)	Gaps:	57/548 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 LESPKN-------------GKHLEQVHQ---------NNNEITE----------SEPL--TWRFW 34
            :|:|:.             ||.|..|::         .|.|:||          ..||  ...|.
Zfish     1 METPREPAGFSKEGLKQLAGKTLGHVYRVIEKRQKPGENIELTEDGRPAQINERKAPLCDCTCFG 65

  Fly    35 RKQRYIVVLLAFFGFFNVYSLRVNLSVAIVAMTENRTVFDADGNVSYQQ--DFPWDSKQKGLILS 97
            ..:|||:.:::..||...:.:|.||.||||:|..|.|: ..:|.:..::  .|.||.:..|||..
Zfish    66 LPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTI-HLNGKIIIKEKAKFNWDPETVGLIHG 129

  Fly    98 SFFYGYILTQFLGGYIGTKIGGNIVFGTGIGSTAILTLLTPMAASHSLEMFLFVRIIEGFFEGVT 162
            |||:|||:||..||||.:::..|.|||..|..|:.|.:..|.||.......:||||::|..||||
Zfish   130 SFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYGCVIFVRILQGLVEGVT 194

  Fly   163 FPGIHAVWARWSPPLERSRMASIAFAGNYAGTVVAMPCSGFLATKYGWESVFYVFGTIGVIWYIT 227
            :|..|.:|::|:|||||||:|:.:|.|:|||.|:|||.:|.|....||.|||||:|..|:.||:.
Zfish   195 YPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGIFWYMF 259

  Fly   228 W-LVFVKAGPELDRFCSKEECDYIQKTIG----YVG-SKHVKHPWRAIFTSMPFYAIMASHFSEN 286
            | ||..::..|.....::|.| ||:::||    .:| :...|.|||..|||||.|||:.::|..:
Zfish   260 WILVSYESPAEHPTITAEERC-YIEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRS 323

  Fly   287 WGFYTLLTQLPSFLRDTLNFDLGKTGILSAVPYLAMGILLAVSGYLADWLQVKGIWTTTQVRRNF 351
            |.||.||...|::..:...|::.|.|:|||:|:|.|.|::.:.|.|||.|:.|.|.:||.||:..
Zfish   324 WTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIM 388

  Fly   352 NCGAFLAQTVFMMLTAYLLDPTWSVVSLTIAVGLGAFAWSGFAVNHLDIAPQHASVLMGIGNTFA 416
            |||.|..:...:::..|......::..|.:|||...||.|||.||||||||::||:||||.|...
Zfish   389 NCGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVG 453

  Fly   417 TIPGIVSPLLTGYVVTNQTSDEWRIIFFISAGIYLVGCVIYWFYCSGDLQEWAKTPEQKAQE--- 478
            |:.|:|.||:.|.:..::|.:||:.:|.|::.::..|.:.|..:.||:.|.|| .||..:.|
Zfish   454 TLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWA-DPELTSDEKCG 517

  Fly   479 -------AEEKAQLQLTQTAGFVNSGAE 499
                   |||..  .:||:.|.:.:.|:
Zfish   518 FIDEDELAEETG--DITQSYGALGAPAK 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MFS9	NP_650889.1	2A0114euk	38..477	CDD:129972	187/446 (42%)
MFS9	NP_650889.1	MFS	42..460	CDD:119392	177/425 (42%)
slc17a6b	NP_001122293.1	2A0114euk	69..509	CDD:129972	185/442 (42%)
slc17a6b	NP_001122293.1	MFS	74..498	CDD:119392	177/425 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2532
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D144672at33208
OrthoFinder	1	1.000	-	-		FOG0000034
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100421
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X201
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.720