DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g2 and EIF3G1

DIOPT Version :9

Sequence 1:	NP_650887.1	Gene:	eIF3g2 / 42422	FlyBaseID:	FBgn0038796	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001154607.1	Gene:	EIF3G1 / 820313	AraportID:	AT3G11400	Length:	321	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	110/320 - (34%)
Similarity:	161/320 - (50%)	Gaps:	55/320 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KTFVTSWADEVDADYVDGLPPSNEYIKGD---FKYVTEYKFNDDGKKVKV---VRTFKIEKQIVP 60
            ||....|.:..:.:.:|.|.|..:.|..|   .|...||||||:..|||:   .|..|:....:.
plant     8 KTSKFRWGEMDEDEDLDFLLPPKQVIGPDENGLKTTIEYKFNDEENKVKITTRTRVRKLASARLN 72

  Fly    61 KAVARRRNWVKFGDSRSDKPGPNSQTTMAS-EEIFMQ---------------------------F 97
            |....||||.||||:.:::.|  |..||.| |||.::                           |
plant    73 KRAMERRNWPKFGDAANEEAG--SHLTMVSTEEILLERPRAPGDQLANHMLASIPEYELKCALTF 135

  Fly    98 IGSK--DFDQTHET-----QLDPGKNIAK-CRICN--GEHWSVNCPYKGTSMDSKTVMETKANAA 152
            :.:.  ..|::..|     ||..|..:.. ||||:  |:||:..||||..:..:...:: |....
plant   136 VAANCTKADESKATGDGLSQLGKGGAVLMVCRICHKKGDHWTSKCPYKDLAAPTDVFID-KPPTG 199

  Fly   153 AAAAISDPSKTGK--YVPPFMKDGGGIS--GSKNWGRGRDRDDSSAVRISNLSESMTETDLEELV 213
            .::.:|....|||  ||||.|:.|...|  ||..    |.|:|.::||::||||...|.||.||.
plant   200 ESSTMSAAPGTGKAAYVPPSMRAGADRSAVGSDM----RRRNDENSVRVTNLSEDTREPDLMELF 260

  Fly   214 KKIGPHTKMYLAREKNSGLCKGFAYVHFKFRQDAAAAIEVLNGHGYDHLILCVEWSKPQP 273
            ...|..|::|:|.::.:|:.:||.:|:|..|:||..||..|||:|||:|||.|||:.|:|
plant   261 HPFGAVTRVYVAIDQKTGVSRGFGFVNFVSREDAQRAINKLNGYGYDNLILRVEWATPRP 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g2	NP_650887.1	eIF3g	28..137	CDD:289149	47/152 (31%)
		RRM	<171..>256	CDD:223796	34/86 (40%)
		RRM_eIF3G_like	194..270	CDD:240854	37/75 (49%)
EIF3G1	NP_001154607.1	eIF3g	35..186	CDD:289149	47/152 (31%)
		RRM	<233..>319	CDD:223796	40/89 (45%)
		RRM_eIF3G_like	241..316	CDD:240854	36/74 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3145
eggNOG	1	0.900	-	-		E1_KOG0122
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	165	1.000	Inparanoid score	I1585
OMA	1	1.010	-	-		QHG55427
OrthoDB	1	1.010	-	-		D1226059at2759
OrthoFinder	1	1.000	-	-		FOG0003558
OrthoInspector	1	1.000	-	-		mtm1122
orthoMCL	1	0.900	-	-		OOG6_102687
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2433
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.780