DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3g2 and eif-3.G

DIOPT Version :9

Sequence 1:	NP_650887.1	Gene:	eIF3g2 / 42422	FlyBaseID:	FBgn0038796	Length:	273	Species:	Drosophila melanogaster
Sequence 2:	NP_001263666.1	Gene:	eif-3.G / 174346	WormBaseID:	WBGene00001230	Length:	262	Species:	Caenorhabditis elegans

Alignment Length:	275	Identity:	102/275 - (37%)
Similarity:	142/275 - (51%)	Gaps:	35/275 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 VTSWADEVDADYVDGLPPSNEYIKGDFKYVTEYKFND-DGKKVKVVRTFKIEKQIVPKAVARRRN 68
            |.|||:.|:.   |..|...|...|.   .||..|.: ||.:.|||..||:..:.|||.||.|:.
Worm    13 VVSWAEAVEQ---DNAPHIQEGADGT---RTETAFTEVDGVRWKVVTQFKVINKRVPKVVADRKK 71

  Fly    69 WVKFGDSRSDKPGPNSQTTMASEEIFMQFIGSKDFDQTHETQLDPGKNIAK------CRICNG-E 126
            |||||..:.:..||...||..:||:.|||..::..:|..:.|.|  |..||      ||.|.| :
Worm    72 WVKFGSCKGEPAGPQVATTYVAEEVDMQFTRNRAGEQILDVQED--KQTAKTTSREHCRHCKGND 134

  Fly   127 HWSVNCPYKGTSMDSKTVMETKANAAAAAAISDPSKTGKYVPPFMKDGGGISGSKNWGRGRDRDD 191
            |||.:||||        ||......|.|...::..:....:.|   ||..|.        |:|.|
Worm   135 HWSTHCPYK--------VMYQLDEEADADKDTEKDRMAMGMRP---DGRQID--------RNRSD 180

  Fly   192 SSAVRISNLSESMTETDLEELVKKIGPHTKMYLAREKNSGLCKGFAYVHFKFRQDAAAAIEVLNG 256
            .:..|::||.:.|.|.:|.:|..|||...::::||:|.:||.||||:|.|:.|.|||.||..||.
Worm   181 ENTCRVTNLPQEMNEDELRDLFGKIGRVIRIFIARDKVTGLPKGFAFVTFESRDDAARAIAELND 245

  Fly   257 HGYDHLILCVEWSKP 271
            ....|::|.|||::|
Worm   246 IRMYHMVLKVEWTRP 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3g2	NP_650887.1	eIF3g	28..137	CDD:289149	48/116 (41%)
		RRM	<171..>256	CDD:223796	34/84 (40%)
		RRM_eIF3G_like	194..270	CDD:240854	34/75 (45%)
eif-3.G	NP_001263666.1	eIF3G	33..143	CDD:240597	46/114 (40%)
		RRM	<176..>260	CDD:223796	37/83 (45%)
		RRM_eIF3G_like	183..259	CDD:240854	34/75 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163159
Domainoid	1	1.000	81	1.000	Domainoid score	I5468
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2784
Inparanoid	1	1.050	149	1.000	Inparanoid score	I2976
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55427
OrthoDB	1	1.010	-	-		D1226059at2759
OrthoFinder	1	1.000	-	-		FOG0003558
OrthoInspector	1	1.000	-	-		otm14665
orthoMCL	1	0.900	-	-		OOG6_102687
Panther	1	1.100	-	-	O	PTHR10352
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R382
SonicParanoid	1	1.000	-	-		X2433
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940