Protein Alignment Tmlh and gbh-2

DIOPT Version :10

• Sequence 1: NP_650886.1
• Gene: Tmlh / 42421
• FlyBaseID: FBgn0038795
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_495793.2
• Gene: gbh-2 / 174358
• WormBaseID: WBGene00001523
• Length: 409
• Species: Caenorhabditis elegans
• Alignment Length: 373
• Identity: 110/373 - (29%)
• Similarity: 186/373 - (49%)
• Gaps: 57/373 - (15%)

  Fly    19 WLRDHCRCVECLNFETNQRRYDVLDLPADIMPLD-VKYDGM--------NLQVQWSDAHKSNYDL 74
            ||||||...:..:..||||:.:.    .||..|. :|:...        :||:.|.|.|:|.:.:
 Worm    48 WLRDHCTSQKLYHLPTNQRKSNC----CDITSLSKIKHSNQVIIDEATNSLQIVWIDGHQSKFKI 108

  Fly    75 -DFIFDSQLERLIGRRSKSTNLTPWNRSIILQNERHLRFPLPQLVSSDNEVRSLVESLVRYGIVF 138
             :.|.:.::|:         |::..|:...|.|.:.|: .:|::..|...::|..::||:||::.
 Worm   109 GNIIREGKVEK---------NVSNDNKIYELWNSKSLK-DVPRISKSTLSLQSFSKNLVKYGVII 163

  Fly   139 IDDVAPTANMTELALRRVFPLMKTFFGEMWTFS-----DNPDHADTAYTKLYLGSHTDNTYFCDA 198
            :|.|..|:..||...:.:.|:..||||:.|.||     |.|.:.||||....:|.|||.|||...
 Worm   164 VDGVEGTSEATEKLCQSLVPVHDTFFGQFWVFSNSATNDEPAYEDTAYGSDEIGPHTDGTYFDQT 228

  Fly   199 AGLQALHCIEHSGSGGENFFVDGLHVVHELKRRYPAAYDVLCSVQVPGEYIEKGEHHY------- 256
            .|:|..||:..:.:||:...||..:...:|:...|..:::||:.::        .|||
 Worm   229 PGIQVFHCLTPAKTGGDTVLVDSFYCAEKLRNESPEDFEILCNTKI--------SHHYLEGSPPG 285

  Fly   257 ---HTA----PIIQVDPLTQEFVQLRLNVYDRAVFNTI-----PQAEMAEFYDSLRQLLLIVRDK 309
               |:.    |:|:.:.. ....|:|.|.||||.|:.:     ..||..:||::..:...|..:.
 Worm   286 SSIHSVSLEKPVIERNSF-GNITQIRFNPYDRAPFSCLNSSEASAAETIKFYEAYEKFSKICHNP 349

  Fly   310 QQQWALKLCPGSIVLFDNWRVLHGREAYTGSRTMSGSYVQRTDFLSKA 357
            .....:.|.|||::..||:|:||.|.::.|.|.|.|.|:.|.:|::||
 Worm   350 DNSIEISLRPGSVIFIDNFRILHSRTSFQGYRQMCGCYLSRDNFMAKA 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmlh	NP_650886.1	CAS_like	19..361	CDD:444731	110/373 (29%)
gbh-2	NP_495793.2	CAS_like	43..402	CDD:444731	110/373 (29%)