Protein Alignment Tmlh and Tmlhe

DIOPT Version :10

• Sequence 1: NP_650886.1
• Gene: Tmlh / 42421
• FlyBaseID: FBgn0038795
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: XP_038954326.1
• Gene: Tmlhe / 170898
• RGDID: 620629
• Length: 445
• Species: Rattus norvegicus
• Alignment Length: 389
• Identity: 126/389 - (32%)
• Similarity: 189/389 - (48%)
• Gaps: 69/389 - (17%)

  Fly     6 HPKTSQSIE---INEFWL--------------RDH--CRCVECLNFETNQRRYDVLDLPADIMPL 51
            ||||.|:..   ::..|.              |.|  |.|                 ||....|
  Rat    92 HPKTKQTRSPSGLSVAWTAAKQSLLDPKAIAHRSHGGCHC-----------------LPTIEPP- 138

  Fly    52 DVKYDGMNLQVQWSDAHKSNYDLDFI----FDSQLERLIGRRSKSTNLTPWNRSIILQNERHLRF 112
              |..|..     .|.|.:.||||::    ::.|.:.:|..|      ..||..:....:
  Rat   139 --KSPGTG-----PDGHVTRYDLDWLVKNSYEGQKQEVIQPR------VLWNAKLYQDAQ----- 185

  Fly   113 PLPQL-----VSSDNEVRSLVESLVRYGIVFIDDVAPTANMTELALRRVFPLMKTFFGEMWTFSD 172
             ||.:     :.:...::..:::.:.|||.|:::|.||...||...|||..:.:|.:|.||.|:.
  Rat   186 -LPSVDFQGFLETKEGLKKFLQNFLLYGIAFVENVPPTQEHTEKLARRVSLIRETIYGRMWYFTS 249

  Fly   173 NPDHADTAYTKLYLGSHTDNTYFCDAAGLQALHCIEHSGSGGENFFVDGLHVVHELKRRYPAAYD 237
            :....|||||||.|..|||.|||.:..|:|..||::|.|:||....|||.:...::.:|.|..:|
  Rat   250 DFSRGDTAYTKLALDRHTDTTYFQEPCGIQVFHCLKHEGTGGRTLLVDGFYAAQQVLQRAPEEFD 314

  Fly   238 VLCSVQVPGEYIEK-GEHHYH---TAPIIQVDPLTQEFVQLRLNVYDRAVFNTIPQAEMAEFYDS 298
            :|..|.:..||||. |:.|.|   ..||:.:.|..:|...:|.|.|||||.||:|...:..:|.:
  Rat   315 LLSQVPLKHEYIENVGQCHNHMIGVGPILNIYPWNKELYLIRYNNYDRAVINTVPYDVVRRWYAA 379

  Fly   299 LRQLLLIVRDKQQQWALKLCPGSIVLFDNWRVLHGREAYTGSRTMSGSYVQRTDFLSKARVLGI 362
            .|.|...:|..:.:..:||.||.::..||||||||||::||.|.:.|.|:.|.|.|:.||:||:
  Rat   380 HRTLTTELRRPENELWVKLKPGKVLFIDNWRVLHGRESFTGYRQLCGCYLTRDDVLNTARILGL 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmlh	NP_650886.1	CAS_like	19..361	CDD:444731	119/370 (32%)
Tmlhe	XP_038954326.1	CAS_like	145..443	CDD:444731	110/309 (36%)