Protein Alignment Tmlh and tmlhe

DIOPT Version :10

• Sequence 1: NP_650886.1
• Gene: Tmlh / 42421
• FlyBaseID: FBgn0038795
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001096300.1
• Gene: tmlhe / 100124877
• XenbaseID: XB-GENE-978203
• Length: 421
• Species: Xenopus tropicalis
• Alignment Length: 364
• Identity: 127/364 - (34%)
• Similarity: 198/364 - (54%)
• Gaps: 27/364 - (7%)

  Fly    13 IEINEFWLRDHCRCVECLNFETNQRRYDVLDLPADIMPLDVKYDGMNLQVQWSDAHKSNYDLDFI 77
            :..|..|||||||...|.|.:||||..|...:..||.|..|:.|...|.:.|.|.|.:.|.|:::
 Frog    69 MRFNYVWLRDHCRSASCYNAKTNQRSLDTATVDLDIQPALVRADETTLYLTWPDGHMTRYGLEWL 133

  Fly    78 ----FDSQLERLIGRRSKSTNLTPWNRSIILQNER-HLRFPLP-----QLVSSDNEVRSLVESLV 132
                ::.|.::|:..|             ||.||| :....:|     :.:.:...:|:.:::.:
 Frog   134 VQNSYEGQKQQLVQPR-------------ILWNERIYKEANVPSVSYSEFLKTSEGLRAFLQNFL 185

  Fly   133 RYGIVFIDDVAPTANMTELALRRVFPLMKTFFGEMWTFSDNPDHADTAYTKLYLGSHTDNTYFCD 197
            .|||.|:|||..|...||....|:..:.:|.:|:||..:.:....|||||||.|..|||.|||.:
 Frog   186 LYGIAFVDDVPATYEDTERVAERISHIRETIYGKMWNLTSDFSRGDTAYTKLALDRHTDTTYFQE 250

  Fly   198 AAGLQALHCIEHSGSGGENFFVDGLHVVHELKRRYPAAYDVLCSVQVPGEYIE----KGEHHYHT 258
            ..|:|..||:.|.|:||....|||.:...:::..||..:::|.:|.:..||||    ...|....
 Frog   251 PCGMQLFHCLRHEGTGGRTLLVDGFYAADQVRHDYPNDFELLSNVPLKHEYIENMAGSNNHMVGI 315

  Fly   259 APIIQVDPLTQEFVQLRLNVYDRAVFNTIPQAEMAEFYDSLRQLLLIVRDKQQQWALKLCPGSIV 323
            .|::.|.|..:|...:|.|.|||||.:|:|...:.::|.:.|:|...:|..:.:..:||.||.::
 Frog   316 GPVLNVYPWNKELYMIRYNNYDRAVISTVPYDIVQQWYIAHRRLTNELRRHENELWVKLKPGKVL 380

  Fly   324 LFDNWRVLHGREAYTGSRTMSGSYVQRTDFLSKARVLGI 362
            ..||||||||||::||.|.:.|.|:.|.|.|:.:|:||:
 Frog   381 FVDNWRVLHGRESFTGYRQICGCYLTRDDVLNTSRLLGL 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tmlh	NP_650886.1	CAS_like	19..361	CDD:444731	124/355 (35%)
tmlhe	NP_001096300.1	CAS_like	70..419	CDD:444731	126/361 (35%)