Protein Alignment Ir92a and grin2ab

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_009304490.1
• Gene: grin2ab / 570493
• ZFINID: ZDB-GENE-070424-223
• Length: 1445
• Species: Danio rerio
• Alignment Length: 517
• Identity: 99/517 - (19%)
• Similarity: 195/517 - (37%)
• Gaps: 103/517 - (19%)

  Fly   198 INFELWTQKFVGAVGNLDALLLDAFLPNETFANRVELYPNKLLNLQRRSLLVGSITYVPYTITNY 262
            :.|.:|.:  ..:.|::||        :|...:.|.|.....:.:....:|.|:      .:.|.
Zfish   375 LKFPVWPR--YNSFGDMDA--------DENHLSIVTLEERPFVIVDDVDILTGT------CMRNS 423

  Fly   263 VPAGQGDVDPIHPQWPNRSLTFDGAEANVMKTFCQ----------VHNCHLRVEAYGADNW-GGI 316
            ||.             .:.:..:..|.:.:|..|:          ..|.....:.|...|. .|.
Zfish   424 VPC-------------RKHIKDNTTEGSYVKKCCKGFCIDILKKIARNVKFTYDLYLVTNGKHGK 475

  Fly   317 YDNESSDGMLGDIYEQRVEMAIGCI---------YNWYDGITET--SHTIARSSVTILGPAPAPL 370
            ..|...:||:|::..::..||:|.:         .::.....||  |..::||:.|:   :|:..
Zfish   476 KINNVWNGMVGEVVYKKAVMAVGSLTINEERSEAIDFSVPFVETGISVMVSRSNGTV---SPSAF 537

  Fly   371 PSWRTNIMPFNNRAWLVL-ISTLVICGTFLYFMKYVS-YRLRYSGTQVKFHH--SRKLEKSMLDI 431
                  :.||:...|::: :..|::....::..:::| .....:..|.|..|  |..:.|::..:
Zfish   538 ------LEPFSASVWVMMFVMLLIVTAIAVFLFEFISPLGFNRNLAQGKDPHGPSFTIGKAVWLL 596

  Fly   432 FALFIQQPSAPLSFDRFAPRFFLATI--LCATITLENIYSGQLKSMLTFPFYSAPVDTIEKWAQS 494
            :.|.... |.|:...|.....|:.::  ..|.|.|.:..:.....|:...|........::..||
Zfish   597 WGLVFNN-SVPVQNPRGTTSKFIVSVWAFFAVIFLASYTANLAAFMIQEEFVDQVTGLSDRKFQS 660

  Fly   495 GWKWSAPSIIWVHTVQSSDLETEQILARNF-EVHDYSYLSNVSFMPNY---GF--GIERLSSGSL 553
            .:.:|.|  ....||.:.  .||:.:.:|: .:|.|        |..|   |.  .:..|.:|.|
Zfish   661 PYSYSPP--FRFGTVPNG--STERNIRKNYPAMHQY--------MVKYHQTGVVDALVSLKTGKL 713

  Fly   554 SVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGWILMPELNKHIRTCQETGLYFHWE-------L 611
            ..  ::...|:.|.:...|    |..:.|:|....:.......|  ..:.|.|  |:       |
Zfish   714 DA--FIYDAAVLNYMAGRD----DGCKLVTIGSGYIFATTGYGI--AMQKGSY--WKRLVDLAIL 768

  Fly   612 EFI-DKYMDKKKQEVLMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALVAELLIH 672
            ..| |..|::.:.:.|..:.:..|.:.....|||.|:||..::||..:|.:....|.|.|.:
Zfish   769 GIIGDGEMEELEAQWLTGICHNEKNEVMSSQLDVDNMAGVFYMLAAAMALSLITFVWEHLFY 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
grin2ab	XP_009304490.1	PBP1_iGluR_NMDA_NR2	25..382	CDD:107373	2/6 (33%)
		ANF_receptor	48..358	CDD:279440
		PBP2_iGluR_NMDA_Nr2	393..790	CDD:270436	81/447 (18%)
		Lig_chan	544..816	CDD:278489	59/294 (20%)
		NMDAR2_C	827..1445	CDD:287527	1/4 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591461
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930