DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir92a and grin3ba

DIOPT Version :9

Sequence 1:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	XP_021323058.1	Gene:	grin3ba / 566411	ZFINID:	ZDB-GENE-070912-354	Length:	1118	Species:	Danio rerio

Alignment Length:	508	Identity:	96/508 - (18%)
Similarity:	172/508 - (33%)	Gaps:	139/508 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   247 LLVGSITYVPYTITNYV------PAGQGDVDP-------IHPQWPNRSLTFDGAEANVMKTFCQ- 297
            |.|.::...|:..|..|      ||||..:||       ::..:.....|...:....|:..|.
Zfish   458 LRVVTLVEHPFVFTREVDEEGQCPAGQLCLDPQTNNSEVLNQLFRELEQTNSSSLPTDMRKCCYG 522

  Fly   298 ---------VHNCHLRVEAY-GADNWGGIYDNESSDGMLGDIYEQRVEMAIGCIYNWYDGITETS 352
                     ..:.|...:.| ..|...|.:......|::||:.....:||          :|..|
Zfish   523 YCIDLLEKLAEDMHFEFDLYIVGDGKYGAWKGGRWSGLVGDLLSGVADMA----------VTSFS 577

  Fly   353 HTIARSSV---------TILG------PAPAPLPSWRTNIMPFNNRAWLVLISTLVICGTFLYFM 402
            ...|||.|         |.||      ...||:.::   :.|.:...|:.:...|.|...|:...
Zfish   578 INSARSRVIDFTSPFFSTSLGILVRSKDTAAPIGAF---MWPLHWSMWVGIFVALHITALFITLY 639

  Fly   403 KYVS---------YRLRYSGTQVKFHHSRKLEKSMLDIFALFIQQPSAPLSFDRFAPRFFLATIL 458
            ::.|         .|:|.      |.:|..|......:|...:...:......||...  |..|.
Zfish   640 EWNSPFGMTPHGRNRIRV------FSYSSALNLCYAILFGRTVASKTPKCWTGRFLMN--LWAIF 696

  Fly   459 CATITLENIYSGQLKSML----TFPFYSAPVDTIEKWAQSGWKWSAPSIIWVHTVQSSDLETEQI 519
            |..:.  :.|:..|.:::    ||...|...|........|:::.        ||:.|  ..|..
Zfish   697 CLLVL--SSYTANLAAVMVGEKTFEEVSGIHDVKLHHPSLGFRFG--------TVRES--SAEDY 749

  Fly   520 LARNF-EVHDYSYLSNVSFMPNYGFGIERLSSGSLSVGDYVSTEALENRIVLHDDLYFDYTRAV- 582
            :.::| |:|:|....|....|:   |:..|.:....:..::..:||           .||..::
Zfish   750 VKKSFPEMHEYMRRFNKPTTPD---GVSTLKTDPPQLDAFIMDKAL-----------LDYEVSID 800

  Fly   583 ------------SIRGW-ILMPELNKHIRTCQETGLYFHWELEFIDKYMDKKKQEVLMDLAN--- 631
                        :|.|: |.:|:.:...|.              :.:|:.:.|.:..||:.:
Zfish   801 ADCKLLTVGKPFAIEGYGIGLPQNSPLTRN--------------VSEYVSRYKSDGYMDMLHDKW 851

  Fly   632 ------GHKVKGAPQALD--VRNIAGALFVLAFGVAFAGCALVAELLIHRMDL 676
                  |.:|....:.|.  :::.:|...:|..|||.|...|:.|....|..|
Zfish   852 YKVVPCGKRVFAVTETLQMGIQHFSGLFVLLCVGVAGALLTLLGEHAFFRFIL 904

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_Type_1	26..428	CDD:324556
grin3ba	XP_021323058.1	PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	83/454 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591703
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930