Protein Alignment Ir92a and grin2bb

DIOPT Version :10

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001121809.1
• Gene: grin2bb / 559976
• ZFINID: ZDB-GENE-061207-27
• Length: 1770
• Species: Danio rerio
• Alignment Length: 554
• Identity: 108/554 - (19%)
• Similarity: 196/554 - (35%)
• Gaps: 131/554 - (23%)

  Fly   212 GNLDALLLDAFLPNETFANR--------VELYPNK---LLNLQRRSLLVG--------------- 250
            ||.:.:|  .:|.|.||..|        .:::|..   |||.:|:...||
Zfish   407 GNPNEVL--RYLMNVTFEGRNLSFSEDGFQMHPKLVIILLNKERQYERVGKWENGSLAMKYHVWP 469

  Fly   251 -------------------SITYVPYTITNYVPAGQGDVDPI-----------HPQWPNRSLTFD 285
                               ::...|:.|..       ||||:           ..|...::||.|
Zfish   470 RFELYSDAEEREDDHLSIVTLEEAPFVIVE-------DVDPLSGTCMRNTVPCRKQLKLQNLTGD 527

  Fly   286 GA--EANVMKTFC------QVHNCHLRVEAYGADNW-GGIYDNESSDGMLGDIYEQRVEMAIGCI 341
            ..  .....|.||      ...:.....:.|...|. .|...|.:.:||:|::..:...||:|.:
Zfish   528 SGIYIKRCCKGFCIDILKKIAKSVKFTYDLYLVTNGKHGKKINGTWNGMVGEVVLKNAHMAVGSL 592

  Fly   342 YNWYDGITETSHTIARSSVTILGPAPAPLPSWRTN--------IMPFNNRAWLVL-ISTLVICGT 397
                 .|.|....:...||..:....:.:.| |:|        :.||:...|::: :..|::...
Zfish   593 -----TINEERSEVIDFSVPFIETGISVMVS-RSNGTVSPSAFLEPFSADVWVMMFVMLLIVSAV 651

  Fly   398 FLYFMKY---VSYRLRYSGTQVKFHHSRKLEKSMLDIFALF------IQQPSAPLSFDRFAPRFF 453
            .::..:|   |.|....:..:.....|..:.|::..::.|.      :|.|....|....:...|
Zfish   652 AVFVFEYFSPVGYNRCLADGREPGGPSFTIGKAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAF 716

  Fly   454 LATILCATITLENIYSGQLKSMLTFPFYSAPVDTI----EKWAQSGWKWSAPSIIWVHTVQSSDL 514
            .|.|..|:.|         .::..|......||.:    :|..|....:|.|  ....||.:.
Zfish   717 FAVIFLASYT---------ANLAAFMIQEEYVDQVTGLSDKKFQHPNDFSPP--FRFGTVPNG-- 768

  Fly   515 ETEQILARNF-EVHDYSYLSNVSF-MPNYGFGIERLSSGSLSVGDYVSTEALENRIVLHDDLYFD 577
            .||:.:..|: |:|.|.    .|| ..|....:..|.||.|..  ::...|:.|.:...|    :
Zfish   769 STERNIRNNYKEMHSYM----TSFHQKNVNEALHSLKSGKLDA--FIYDAAVLNYMAGRD----E 823

  Fly   578 YTRAVSIRGWILMPELNKHIRTCQETGLYFHWELEFIDKYMDKKKQEV----LMDLANGHKVKGA 638
            ..:.|:|....:.......|...:::|.....:|..:..:.|.:.:|:    |..:.:..|.:..
Zfish   824 GCKLVTIGSGYIFATTGYGIAIQKDSGWKRAVDLAILQLFGDGEMEELEALWLTGICHNEKNEVM 888

  Fly   639 PQALDVRNIAGALFVLAFGVAFAGCALVAELLIH 672
            ...|||.|:||..::|...:|.:....:||.|.:
Zfish   889 SSQLDVDNMAGVFYMLGAAMALSLITFIAEHLFY 922

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
grin2bb	NP_001121809.1	PBP1_iGluR_NMDA_NR2	107..465	CDD:380601	15/59 (25%)
		PBP2_iGluR_NMDA_Nr2	482..882	CDD:270436	81/435 (19%)
		NMDAR2_C	919..1770	CDD:463148	1/4 (25%)