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Protein Alignment Ir92a and Grik2

DIOPT Version :9

Sequence 1:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_062182.1	Gene:	Grik2 / 54257	RGDID:	2733	Length:	908	Species:	Rattus norvegicus

Alignment Length:	805	Identity:	153/805 - (19%)
Similarity:	267/805 - (33%)	Gaps:	247/805 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LQPLVMHLSQLLRIIVGQYFAEFPSILIVYNNSASTTPLQLEYLSA-----LELVLREL------ 56
            |.|....||:.:..:| |:| ::.::.:||::|.....|| |.:.|     |.|.:|:|
  Rat   149 LYPDFSSLSRAILDLV-QFF-KWKTVTVVYDDSTGLIRLQ-ELIKAPSRYNLRLKIRQLPADTKD 210

  Fly    57 SKPI-----RLQWINVAFLKDLNDLEDQVMGALNSSVTEGFITILSQTHHFIHA----------- 105
            :||:     |.:..:|.|  |.:  .:...|.|..::..|.:|   :.:|:|..
  Rat   211 AKPLLKEMKRGKEFHVIF--DCS--HEMAAGILKQALAMGMMT---EYYHYIFTTLDLFALDVEP 268

  Fly   106 -RYYATRNANVRLKDKRYLFLCEDESPAELLCMDILQFYPHHLMVRPGTETAPTGPTGPHPD--- 166
             ||........|:.:...   .:..|..|...|:.||              ||     |.||
  Rat   269 YRYSGVNMTGFRILNTEN---TQVSSIIEKWSMERLQ--------------AP-----PKPDSGL 311

  Fly   167 ----------------------------------------PRRGGGASVSTKNKDDGEGGAG--- 188
                                                    |.|.|...:|...:...||..|
  Rat   312 LDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPWRFGTRFMSLIKEAHWEGLTGRIT 376

  Fly   189 -NKTTSPYRDINFELWTQKFVG--AVGNLDALLLDAFLPNETFANRVELYPNKLLN----LQRRS 246
             |||.....|.:.::.:.|..|  .:|..|.         .:..|..|....|..|    |..||
  Rat   377 FNKTNGLRTDFDLDVISLKEEGLEKIGTWDP---------ASGLNMTESQKGKPANITDSLSNRS 432

  Fly   247 LLVGSITYVPYTITNYVPAGQGDVDPIHPQWPNRSLTFDGAEANVMKTFCQVHNCHLRVEAYGAD 311
            |:|.:|...||.:..     :.|    .|.:.|.  .|:|...::::....:......:......
  Rat   433 LIVTTILEEPYVLFK-----KSD----KPLYGND--RFEGYCIDLLRELSTILGFTYEIRLVEDG 486

  Fly   312 NWGGIYD-NESSDGMLGDIYEQRVEMAIGCIYNWY--DGITETSHTIARSSVTILGPAP-APLPS 372
            .:|...| |...:||:.::.:.:.::|:..:...|  :.:.:.|.......::||...| ...|.
  Rat   487 KYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPNGTNPG 551

  Fly   373 WRTNIMPFNNRAWL-VLISTL-VICGTFLY--FMKYVSYRLR--YSGTQVKFHHSRKLEKSMLDI 431
            ..:.:.|.:...|: ||::.| |.|..|:.  |..|..|...  ...:.|..::...|......:
  Rat   552 VFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGV 616

  Fly   432 FALFIQ----QPSAPLSFDRFAPRFFLATILCA------TITLENIYSGQLKSMLTFPFYSAPVD 486
            .||..|    .|.|            |:|.:..      |:.:.:.|:..|.:.||.....:|:|
  Rat   617 GALMRQGSELMPKA------------LSTRIVGGIWWFFTLIIISSYTANLAAFLTVERMESPID 669

  Fly   487 TIEKWAQ------------------SGWKWSAPSIIWVH--------TVQSSDLETEQILARNFE 525
            :.:..|:                  ...|.|....:|..        .|:|::...:::|
  Rat   670 SADDLAKQTKIEYGAVEDGATMTFFKKSKISTYDKMWAFMSSRRQSVLVKSNEEGIQRVL----- 729

  Fly   526 VHDYSYL---SNVSFMPNYGFGIERLSSGSLSVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGW 587
            ..||::|   :.:.|:......:.::.....|.|..|.|           .:...|...::|.
  Rat   730 TSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGT-----------PMGSPYRDKITIA-- 781

  Fly   588 ILMPELNKHIRTCQETGLYFHWELEFIDKYMDKKKQEVLMDLANGHKVKGAPQ-------ALDVR 645
                     |...||.|          ..:|.|:|         ..:..|.|:       ||.|:
  Rat   782 ---------ILQLQEEG----------KLHMMKEK---------WWRGNGCPEEESKEASALGVQ 818

  Fly   646 NIAGALFVLAFGVAFAGCALVAELL 670
            ||.|...|||.|:..:....|.|.|
  Rat   819 NIGGIFIVLAAGLVLSVFVAVGEFL 843

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.