DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ir92a and CG11155

DIOPT Version :9

Sequence 1:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_651941.2	Gene:	CG11155 / 43822	FlyBaseID:	FBgn0039927	Length:	910	Species:	Drosophila melanogaster

Alignment Length:	717	Identity:	139/717 - (19%)
Similarity:	255/717 - (35%)	Gaps:	177/717 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VYNNSASTTPLQLE--YLSALELVLRELSKPIRLQWINVAFLKDLNDLEDQVMGALNSSV----- 88
            :|.....|.|..::  :.|.|:|.:.:    .|..::...|..:..||||....::|.:.
  Fly   221 IYKIIVDTNPSHIKSFFRSILQLQMND----HRYHYMFTTFDLETYDLEDFRYNSVNITAFRLVD 281

  Fly    89 --TEGFITILSQTHHFIH--------ARYYATRNANVRLKDKRYLFLCEDESPAELLCMDILQ-F 142
              ::.::.:::|.....|        :.|..|.:|  .:.|..|.|    .:....|.:|..| |
  Fly   282 VDSKRYLEVINQMQKLQHNGLDTINGSPYIQTESA--LMFDSVYAF----ANGLHFLNLDNHQNF 340

  Fly   143 YPHHLMVRPGTETAPTGPTGPHPDPRRGGGASVSTKNKDDGEGGAGNKTTSPYRDINFELWTQKF 207
            |..:|                         :..|.:..:||        .|.|..||..: |...
  Fly   341 YIKNL-------------------------SCTSDQTWNDG--------ISLYNQINAAI-TDGL 371

  Fly   208 VGAV----GNLDALLLDAF-LPNETFANRVELYPNKLLNLQRRSLL----VGSITYV-------P 256
            .|.|    |..:...||.. |..|........:|:..:|:...:..    :.:||.|       |
  Fly   372 TGTVQFVEGRRNIFKLDILKLKQEKIQKVGYWHPDDGVNISDPTAFYDSNIANITLVVMTREERP 436

  Fly   257 YTITNYVPAGQGDVDPIHPQWPNRSLT----FDGAEANVMKTFCQVHNCHLRVEAYGADNWGGIY 317
            |.:..                .:::||    |:|...:::|..........::|.. .||..|:|
  Fly   437 YVMVK----------------EDKNLTGNLRFEGFCIDLLKAIATQVGFQYKIELV-PDNMYGVY 484

  Fly   318 --DNESSDGMLGDIYEQRVEMAIGCIYNWY--DGITETSHTIARSSVTILGPAPAPLPSWRTNIM 378
              :..|.:|::.::.|:|.::|:..:...|  :.:.:.:.......:.||...|...|   |.:.
  Fly   485 IPETNSWNGIVQELMERRADLAVASMTINYARESVIDFTKPFMNLGIGILFKVPTSQP---TRLF 546

  Fly   379 PFNN----RAWLVLISTLVICGTFLYFM-KYVSYRLR-----YSGTQVKFHHSRKLEKSMLDIFA 433
            .|.|    ..||.:::..::....|:.| ::..|..:     |..|.: ..:...:..|...|..
  Fly   547 SFMNPLAIEIWLYVLAAYILVSFALFVMARFSPYEWKNPHPCYKETDI-VENQFSISNSFWFITG 610

  Fly   434 LFIQQPSAPLSFDRFAPR------FFLATILCATITLENIYSGQLKSMLTFPFYSAPVDTIEKWA 492
            .|::|.|. |:....:.|      ||...|:.::      |:..|.:.||.....:|:::....|
  Fly   611 TFLRQGSG-LNPKATSTRIVGGCWFFFCLIIISS------YTANLAAFLTVERMISPIESASDLA 668

  Fly   493 QSGWKWSAPSIIWVHTVQSSDLETEQILARNFEVHDYS----YLSN---VSFMPNYGFGIERLSS 550
            :.       :.|...|::.....|   ..|:.::..|.    |:.|   ..|:..|..||:|:..
  Fly   669 EQ-------TEISYGTLEGGSTMT---FFRDSKIGIYQKMWRYMENRKTAVFVKTYEDGIKRVME 723

  Fly   551 GSLSVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGW-ILMP-------ELNKHIRTCQETG--- 604
            ||.:   ::....:.:..|..|.........:..:|: |..|       :::..|...||.|
  Fly   724 GSYA---FLMESTMLDYAVQRDCNLTQIGGLLDSKGYGIATPKGSPWRDKISLAILELQEKGIIQ 785

  Fly   605 -LYFHWELEFID--KYMDKKKQEVLMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALV 666
             ||..|.....|  ...||.|:    ..||         ||.|.||.|...||..|:|.|....:
  Fly   786 ILYDKWWKNTGDVCNRDDKSKE----SKAN---------ALGVENIGGVFVVLLCGLALAVVVAI 837

  Fly   667 AE 668
            .|
  Fly   838 FE 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
CG11155	NP_651941.2	PBP1_iGluR_Kainate	44..410	CDD:107377	43/232 (19%)
		ANF_receptor	61..393	CDD:279440	40/215 (19%)
		PBP2_iGluR_Kainate	424..793	CDD:270432	77/409 (19%)
		Lig_chan	555..829	CDD:278489	63/307 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463072
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840