Protein Alignment Ir92a and Ekar

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 759
• Identity: 140/759 - (18%)
• Similarity: 263/759 - (34%)
• Gaps: 216/759 - (28%)

  Fly     8 MHLSQLLRIIVGQYFAEFPS----ILIVYNNSASTTPLQLEYLSALELVLRELSKPIRLQWINVA 68
            :|:.|:.|........||..    .:|:..||...:.|       |:.:|::.....:..::..:
  Fly   173 VHMRQVSRDSYVSALNEFKGKEIHNIIIDTNSNGISIL-------LKNILQQQMNEYKYHYLFTS 230

  Fly    69 FLKDLNDLEDQVMGALN-------SSVTEGFITILSQ----THHFIHARYYATRNANVRLKDKRY 122
            |..:..||||.....:|       .:...|...||..    :||.....|     .|:.:|....
  Fly   231 FDLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPY-----LNLHIKKSTI 290

  Fly   123 LFLCEDESPAELLCMDILQFYPHHLMVRPGTETAPTGPTGPHPDPRRGGGASVSTKNKDDGEGGA 187
            |    :..||  |..|.:..:...|.....:.:...              .::|.:.::..:||.
  Fly   291 L----ESEPA--LMFDSVYVFAIGLQTLEQSHSLTL--------------LNISCEEENSWDGGL 335

  Fly   188 G----------NKTTSP--YRD---INFEL---------------WTQKFVGAVGNLD----ALL 218
            .          ...|.|  ::|   :.|:|               ||..     |:|:    ::.
  Fly   336 SLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQHSIVKVGEWTPH-----GHLNITEPSMF 395

  Fly   219 LDAFLPNETFANRVELYPNKLLNLQRRSLLVGSITYVPYTITNYVPAGQGDVDPIHPQWPNRSLT 283
            .||...|.|                   |:|.:|...||.:.:|                .::.|
  Fly   396 FDAGSMNVT-------------------LVVITILETPYVMMHY----------------GKNFT 425

  Fly   284 ----FDGAEANVMKTFCQVHNCHLRVE-----AYGADNWGGIYDNESSD--GMLGDIYEQRVEMA 337
                |.|...::::|..:.......::     .|||.      |.|:.:  ||:..:.:.:.::|
  Fly   426 GNERFYGFCVDILETISREVGFDYILDLVPDRKYGAK------DPETGEWNGMVAQLMKYKADLA 484

  Fly   338 IGCIYNWY--DGITETSHTIARSSVTILGPAPAPLPSWRTNIMPFNN----RAWLVLISTLVICG 396
            :|.:...|  :.:.:.:.......::||...|...|   |.:..|.|    ..|:.::....:..
  Fly   485 VGSMTITYARESVIDFTKPFMNLGISILFKVPTSEP---TRLFSFMNPLAIEIWIYVLIAYFLVS 546

  Fly   397 TFLYFMKYVSYRLRYSGTQVKFHHSRKLEK-------SMLDIF----ALFIQQPSAPLSFDRFAP 450
            ..:|.:.      :.|..:.|..::..||.       |:.|.|    ..|:||     |.|.: |
  Fly   547 LCIYIVG------KLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQ-----SPDIY-P 599

  Fly   451 RFFLATILCAT-----ITLENIYSGQLKSMLTFPFYSAPVDTIEKWAQS-----GWKWSAPSIIW 505
            |.....|:.:|     :.:...|:..|.:.||......|::..|..|..     |...|..::.:
  Fly   600 RAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTF 664

  Fly   506 VHTVQSSDLETEQILARNFEVHDYSYLSNVSFMPNYGFGIERLSSGSLSVGDYVSTEALENRIVL 570
               .:.|.:||.:.:.|:.:....|     :|...|..||:|::.|:.:   ::....:.:.||.
  Fly   665 ---FRDSVIETYKKIWRSMDNKKPS-----AFTTTYEDGIKRVNQGNYA---FLMESTMLDYIVQ 718

  Fly   571 HDDLYFDYTRAVSIRGW-ILMP-------ELNKHIRTCQETG----LYFHWELEFIDKYMDKKKQ 623
            .|.........:..:|: |..|       :::..|...||.|    ||..| .:..|:...:|
  Fly   719 RDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKW-WKNTDETCTRK-- 780

  Fly   624 EVLMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALVA 667
                   |..|...| .:|.:.:|.|...||..|:..|  |:||
  Fly   781 -------NTSKQSKA-NSLGLESIGGVFVVLIAGIIVA--AVVA 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	42/251 (17%)
		ANF_receptor	39..371	CDD:279440	39/229 (17%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	80/436 (18%)
		Lig_chan	533..807	CDD:278489	61/307 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463073
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840