DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir92a and Ir93a

DIOPT Version :9

Sequence 1:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_650924.3	Gene:	Ir93a / 42471	FlyBaseID:	FBgn0259215	Length:	868	Species:	Drosophila melanogaster

Alignment Length:	768	Identity:	134/768 - (17%)
Similarity:	236/768 - (30%)	Gaps:	248/768 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VMHLSQLLRII-VGQYFAEFPSILIVYNNSASTTPLQLEYLSALELVLRELSKPIRLQWINVAFL 70
            ::.:::.|.:. ||..:..|...::..:..|.|..:.|:                  :..|:||.
  Fly   246 IIEIAETLNMFHVGNQWMIFVLDMVARDFDAGTVTINLD------------------EGANIAFA 292

  Fly    71 KDLNDLEDQVMGALNSSVTE------GFITILSQTHHFIHARYYATRNANVRLKDKRY--LFLCE 127
              ||:.:.....:||.:::|      ..|:.::.....|:.          .:.|:.:  :...:
  Fly   293 --LNETDPNCQDSLNCTISEISLALVNAISKITVEEESIYG----------EISDEEWEAIRFTK 345

  Fly   128 DESPAELLCMDILQFYPHHL--------MVRPGTETAPTGPTGPHPDPRRGGGASVSTKNKDDGE 184
            .|..||     ||::....|        ..|...|||.|           .|.:..:.|.:...:
  Fly   346 QEKQAE-----ILEYMKEFLKTNAKCSSCARWRVETAIT-----------WGKSQENRKFRSTPQ 394

  Fly   185 GGAGNKTTSPYRDINFELWTQKFVGAVGNLDALLLDAFLPNETFANRVELYPNKLLNLQRRSLLV 249
            ..|.|:.   :..||...||                   |...|..:...:|
  Fly   395 RDAKNRN---FEFINIGYWT-------------------PVLGFVCQELAFP------------- 424

  Fly   250 GSITYVPYTITNYVPAGQGDVDPIH-PQWPNRSLT---------FDGAEANVMKTFCQVHNCHLR 304
                ::.:...|...    |:..:| |.|  :.||         ..|....::|...:..|  ..
  Fly   425 ----HIEHHFRNITM----DILTVHNPPW--QILTKNSNGVIVEHKGIVMEIVKELSRALN--FS 477

  Fly   305 VEAYGADNW----------GGIYDNESSDGMLGDIYEQRVEMAIGCIYNWYDGITETSHTIARSS 359
            ...:.|..|          ||   || ||.::|       .|.....|...:.:......||..:
  Fly   478 YYLHEASAWKEEDSLSTSAGG---NE-SDELVG-------SMTFRIPYRVVEMVQGNQFFIAAVA 531

  Fly   360 VTILGPAPAPL-----------------PSWRTNI----MPFNNRAWLVLISTLVICGTFLYFMK 403
            .|:..|...|.                 |...:.|    .||....|..|:..:::....||.:.
  Fly   532 ATVEDPDQKPFNYTQPISVQKYSFITRKPDEVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAIN 596

  Fly   404 YVS--YRLRYSGTQVKFHHSRKLEKSMLDIFALFIQQ-----PSAPLSFDRFAPRFFLATILCAT 461
            .::  ..:|..|...       ::.....||...:||     |:|  ...|....|:...:
  Fly   597 RLAPLKEMRIVGLST-------VKSCFWYIFGALLQQGGMYLPTA--DSGRLVVGFWWIVV---- 648

  Fly   462 ITLENIYSGQLKSMLTFPFYSAPVDTIEKW------AQSGWKWSAPSIIWVHTVQSSDLETEQIL 520
            |.|...|.|.|.:.||||.:...||.:.:.      .|.|.:   ....:...|||:..|
  Fly   649 IVLVTTYCGNLVAFLTFPKFQPGVDYLNQLEDHKDIVQYGLR---NGTFFERYVQSTTRE----- 705

  Fly   521 ARNFEVHDYS-YLSNVSFMPNYGFG----IERLSSGS-LSVGDYVSTEALENR---------IVL 570
                   |:. ||.....   ||..    ||.:..|. :::...::.:.:..|         ..|
  Fly   706 -------DFKHYLERAKI---YGSAQEEDIEAVKRGERINIDWRINLQLIVQRHFEREKECHFAL 760

  Fly   571 HDDLYFDYTRAVSIRGWILMPE-------LNKHIRTCQETGLYFHW---ELEFIDKYMDKKKQEV 625
            ..:.:.|...|      :::|.       :|:||::....|....|   .|....|...|..|..
  Fly   761 GRESFVDEQIA------MIVPAQSAYLHLVNRHIKSMFRMGFIERWHQMNLPSAGKCNGKSAQRQ 819

  Fly   626 LMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALVAELLIHRMDLSK 678
            :    ..|||       ::.::.|...||..|...|...:..|....|...|:
  Fly   820 V----TNHKV-------NMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFRASR 861

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:328725	57/302 (19%)
Ir93a	NP_650924.3	Lig_chan	576..836	CDD:306551	57/307 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840