DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir92a and GluRIA

DIOPT Version :9

Sequence 1:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_476855.1	Gene:	GluRIA / 38742	FlyBaseID:	FBgn0004619	Length:	991	Species:	Drosophila melanogaster

Alignment Length:	428	Identity:	88/428 - (20%)
Similarity:	145/428 - (33%)	Gaps:	114/428 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 YGADNWGGIYDNESSDGMLGDIYEQRVEMAIGC--IYNWYDGITETSHTIARSSVTILGPAPA-P 369
            |||:|.   |.....|||:|::..:..::||..  |....:.:.:.|.......::|:...|. .
  Fly   537 YGAENQ---YAPGGWDGMVGELIRKEADIAISAMTITAERERVIDFSKPFMTLGISIMIKKPVKQ 598

  Fly   370 LPSWRTNIMPFNNRAWLVLISTLVICGTFLYFM-KYVSYRLR----------------------Y 411
            .|...:.:.|.:...|:.:|.:.|.....|||: ::..|..|                      .
  Fly   599 TPGVFSFLNPLSQEIWISVILSYVGVSFVLYFVTRFPPYEWRIVRRPQADSTAQQPPGIIGGATL 663

  Fly   412 SGTQVKFHHSRKLEKSMLDIF----ALFIQQPSAPLSFDRFAPRFFLATILCATITLENIYSGQL 472
            |..|.........|.:||:.|    |.|:|| ...::....|.|...|.....||.|.:.|:..|
  Fly   664 SEPQAHVPPVPPNEFTMLNSFWYSLAAFMQQ-GCDITPPSIAGRIAAAVWWFFTIILISSYTANL 727

  Fly   473 KSMLTFPFYSAPVDTIEKWAQ------------SGWKWSAPSIIWVHTVQSSDLETEQILARNFE 525
            .:.||.....||:.|.|....            |.|::...|.|.:|......:...|    :..
  Fly   728 AAFLTVERMVAPIKTPEDLTMQTDVNYGTLLYGSTWEFFRRSQIGLHNKMWEYMNANQ----HHS 788

  Fly   526 VHDYSYLSNVSFMPNYGFGIERLSSGSLSVGDY-VSTEALENRIVLHDDLYFDYTRA-------- 581
            ||.|..            ||.|:..   |.|.| :..|:.:|          :|..|
  Fly   789 VHTYDE------------GIRRVRQ---SKGKYALLVESPKN----------EYVNARPPCDTMK 828

  Fly   582 ----VSIRGW--------ILMPELNKHIRTCQETG----LYFHWELEFIDKYMDKKKQEVLMDLA 630
                :..:|:        .|...||:.:.|.:|.|    :...|       :.||.:       .
  Fly   829 VGRNIDTKGFGVATPIGSPLRKRLNEAVLTLKENGELLRIRNKW-------WFDKTE-------C 879

  Fly   631 NGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALVAE 668
            |..:....|..|.:.|:||..::|..|:..|....:.|
  Fly   880 NLDQETSTPNELSLSNVAGIYYILIGGLLLAVIVAIME 917

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
GluRIA	NP_476855.1	PBP1_iGluR_AMPA	41..453	CDD:107375
		ANF_receptor	53..434	CDD:279440
		PBP2_iGluR_AMPA	477..879	CDD:270433	78/388 (20%)
		Lig_chan	612..907	CDD:278489	68/338 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462556
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840