Protein Alignment Ir92a and gria4b

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_997917.2
• Gene: gria4b / 336069
• ZFINID: ZDB-GENE-030131-8013
• Length: 904
• Species: Danio rerio
• Alignment Length: 584
• Identity: 108/584 - (18%)
• Similarity: 196/584 - (33%)
• Gaps: 199/584 - (34%)

  Fly   184 EGGAGNKTTSPY-RDIN-----FELWTQ--KFVGAVGNLDALLL---DAFLPNETFANRVELYPN 237
            :|..||.....| |.:|     |||.:.  :.:|...:.|.|:|   .|.|||||
Zfish   355 QGLTGNVQFDHYGRRVNYTMDVFELKSNGPRRIGYWNDADKLVLTQDHALLPNET---------- 409

  Fly   238 KLLNLQRRSLLVGSITYVPYTITNYVPAGQGDVDPIHPQWPNRSLTFDGAE----------ANVM 292
              ..::.|:::|.:|...||.:             :...|.    .::|.|          :.:.
Zfish   410 --SGMENRTVIVTTIMEGPYVM-------------LKKNWE----MYEGNEQYEGYCVDLASEIA 455

  Fly   293 KTFCQVHNCHLRVE---AYGADNWGGIYDNESS--DGMLGDIYEQRVEMAIGCIYNWYDGITETS 352
            |        |:..:   :...|...|..|.|:.  :||:|::...:.|:|:..:          :
Zfish   456 K--------HIGFKYKISIVPDGKYGARDPETKIWNGMVGELVYGKAEIAVAPL----------T 502

  Fly   353 HTIARSSVTILGPAPAPLPSWRTNIM----------------PFNNRAWLVLISTLVICGTFLYF 401
            .|:.|..|....   .|..|...:||                |.....|:.::...:.....|:.
Zfish   503 ITLVREEVIDFS---KPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFL 564

  Fly   402 MKYVSYRLRYSGTQVKFHHSRKLEK------------------SMLDIFALFIQQPSAPLSFDRF 448
            :.      |:|..:   .|:.:.|:                  |:......|:||..      ..
Zfish   565 VS------RFSPYE---WHTEEPEEGTDGLPSDQPPNEFGIFNSLWFSLGAFMQQGC------DI 614

  Fly   449 APRFFLATILCA-----TITLENIYSGQLKSMLTFPFYSAPVDTIEKWAQSGWKWSAPSIIWVHT 508
            :||.....|:..     |:.:.:.|:..|.:.||.....:|:::.|..|:.       :.|...|
Zfish   615 SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQ-------TDIAYGT 672

  Fly   509 VQSSDLETEQILARN-FEVHD--YSYLSNVS---FMPNYGFGIERLSSGSLSVGDYVSTEALENR 567
            :.|.  .|::...|: ..|::  :||:.:..   |......|:.|:..   |.|.|.
Zfish   673 LDSG--STKEFFRRSKIAVYEKMWSYMKSAEPTVFTKTTAEGVARVRK---SKGKYA-------- 724

  Fly   568 IVLHDDLYFDYTR--------------------AVSIRGWILMPELNKHIRTCQETGLYFHWELE 612
             .|.:....:||.                    ..:.:|..|...:|..:....|.||
Zfish   725 -FLLESTMNEYTEQRKPCDTMKVGGNLDSKGYGVATPKGSQLRSAVNLAVLKLNEQGL------- 781

  Fly   613 FIDKYMDKKKQEVLMDL------ANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALVAELL 670
                 :||.|.:...|.      ..|.|.|.: |||.:.|:||..::|..|:   |.|::..|:
Zfish   782 -----LDKLKNKWWYDKGECGSGGGGEKDKSS-QALSLSNVAGVFYILVGGL---GLAMLVALI 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
gria4b	NP_997917.2	Periplasmic_Binding_Protein_Type_1	28..398	CDD:324556	12/42 (29%)
		PBP2_iGluR_AMPA_GluR4	414..793	CDD:270445	74/464 (16%)
		Lig_chan	546..827	CDD:306551	58/329 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591677
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840