Protein Alignment Ir92a and Gria4

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001106655.1
• Gene: Gria4 / 29629
• RGDID: 61863
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 108/600 - (18%)
• Similarity: 205/600 - (34%)
• Gaps: 186/600 - (31%)

  Fly   157 PTGPTGPHPDPRRGGGASVSTKNKDDGEGGAGNKTTSPY-RDIN-----FELWT--QKFVGAVGN 213
            |..|.|...|..|       |..:...:|..||.....| |.:|     |||.:  .:.||...:
  Rat   335 PAAPWGQGIDMER-------TLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWND 392

  Fly   214 LDALLLDAFLP---NETFANRVELYPNKLLNLQRRSLLVGSITYVPYTITNYVPAGQGDVDPIHP 275
            :|.|:|...:|   |:|.|            ::.|:::|.:|...||.:
  Rat   393 MDKLVLIQDMPTLGNDTAA------------IENRTVVVTTIMESPYVM---------------- 429

  Fly   276 QWPNRSLTFDGAE----------ANVMKTFCQVHNCHLRVE---------AYGADNWGGIYDNES 321
             :......|:|.:          :.:.|        |:.::         .|||.:    .|.:.
  Rat   430 -YKKNHEMFEGNDKYEGYCVDLASEIAK--------HIGIKYKIAIVPDGKYGARD----ADTKI 481

  Fly   322 SDGMLGDIYEQRVEMAIGCIYNWYDGITETSHTIARSSVTILGPAPAPLPSWRTNIM-------- 378
            .:||:|::...:.|:||..:          :.|:.|..|....   .|..|...:||
  Rat   482 WNGMVGELVYGKAEIAIAPL----------TITLVREEVIDFS---KPFMSLGISIMIKKPQKSK 533

  Fly   379 --------PFNNRAWLVLISTLVICGTFLYFMKYVSYRLRYSGTQVKFHHSRKLE---------- 425
                    |.....|:.::...:.....|:.:.      |:|..:   .|:.:.|
  Rat   534 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS------RFSPYE---WHTEEPEDGKEGPSDQP 589

  Fly   426 -------KSMLDIFALFIQQPSAPLSFDRFAPRFFLATILCA-----TITLENIYSGQLKSMLTF 478
                   .|:......|:||..      ..:||.....|:..     |:.:.:.|:..|.:.||.
  Rat   590 PNEFGIFNSLWFSLGAFMQQGC------DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 648

  Fly   479 PFYSAPVDTIEKWAQSGWKWSAPSIIWVHTVQSSDLETEQILARN-FEVHD--YSYLSNVS---F 537
            ....:|:::.|..|:.       :.|...|:.|.  .|::...|: ..|::  ::|:.:..   |
  Rat   649 ERMVSPIESAEDLAKQ-------TEIAYGTLDSG--STKEFFRRSKIAVYEKMWTYMRSAEPSVF 704

  Fly   538 MPNYGFGIERL--SSGSL------SVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGWILMPELN 594
            ......|:.|:  |.|..      ::.:|:......:.:.:..:|........:.:|..|...:|
  Rat   705 TRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRNAVN 769

  Fly   595 KHIRTCQETGLYFHWELEFIDKYMDKKKQEVLMDL----ANGHKVKGAPQALDVRNIAGALFVLA 655
            ..:....|.||            :||.|.:...|.    :.|...|....||.:.|:||..::|.
  Rat   770 LAVLKLNEQGL------------LDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILV 822

  Fly   656 FGVAFAGCALVAELL 670
            .|:   |.|::..|:
  Rat   823 GGL---GLAMLVALI 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Gria4	NP_001106655.1	PBP1_iGluR_AMPA_GluR4	28..398	CDD:107383	19/69 (28%)
		ANF_receptor	39..380	CDD:279440	14/51 (27%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	72/458 (16%)
		Lig_chan	546..825	CDD:278489	53/314 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350116
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840