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Protein Alignment Ir92a and Grik1

DIOPT Version :9

Sequence 1:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_001104587.1	Gene:	Grik1 / 29559	RGDID:	2732	Length:	949	Species:	Rattus norvegicus

Alignment Length:	844	Identity:	165/844 - (19%)
Similarity:	275/844 - (32%)	Gaps:	311/844 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LQPLVMHLSQLLRIIVGQYFAEFPSILIVYNNSASTTPLQLEYLSA-----LELVLREL------ 56
            |.|....:|:.:..:|..|  .:.::.:||.:|.....|| |.:.|     :::.:|:|
  Rat   150 LYPDYAAISRAVLDLVLYY--NWKTVTVVYEDSTGLIRLQ-ELIKAPSRYNIKIKIRQLPPANKD 211

  Fly    57 SKPIRLQWINVAFLKDLN---------DLEDQVMGALNSSVTEGFITILSQTHHFIHARYYAT-- 110
            :||:         ||::.         |...:....:...:.  |:.::::.:|:    ::.|
  Rat   212 AKPL---------LKEMKKSKEFYVIFDCSHETAAEILKQIL--FMGMMTEYYHY----FFTTLD 261

  Fly   111 ---------RNANVRLKDKRYLFLCEDESP-----AELLCMDILQFYPHHLMVRPGTETAPTGPT 161
                     |.:.|.:...|.|.:   ::|     .|...|:.||..|     ||.|.......|
  Rat   262 LFALDLELYRYSGVNMTGFRLLNI---DNPHVSSIIEKWSMERLQAPP-----RPETGLLDGMMT 318

  Fly   162 --------------------------------------GPH-----PDPRRGGGASVSTKNKDDG 183
                                                  ||.     .:.|..|.....|.||.||
  Rat   319 TEAALMYDAVYMVAIASHRASQLTVSSLQCHRHKPWRLGPRFMNLIKEARWDGLTGRITFNKTDG 383

  Fly   184 -------------EGGAGNKTTSPYRDINFELWTQKFVGAVGNLDALLLDAFLPNETFANRVELY 235
                         |.|. .|.:.......:::|  |.:|...:...|       |.|..|| :..
  Rat   384 LRKDFDLDIISLKEEGT-EKASGEVSKHLYKVW--KKIGIWNSNSGL-------NMTDGNR-DRS 437

  Fly   236 PNKLLNLQRRSLLVGSITYVPYTITNYVPAGQGDVDPIHPQWPNRSLTFDGAEANVMKTFCQVHN 300
            .|...:|..|:|:|.:|...||.:..     :.|    .|.:.|.  .|:|...:::|....:..
  Rat   438 NNITDSLANRTLIVTTILEEPYVMYR-----KSD----KPLYGND--RFEGYCLDLLKELSNILG 491

  Fly   301 CHLRVE-----AYGADNWGGIYDNESSDGMLGDIYEQRVEMAIGCIYNWY--DGITETSHTIARS 358
            ....|:     .|||.|     |....:||:.::.:.|.::|:..:...|  :.:.:.|......
  Rat   492 FLYDVKLVPDGKYGAQN-----DKGEWNGMVKELIDHRADLAVAPLTITYVREKVIDFSKPFMTL 551

  Fly   359 SVTILGPAP-APLPSWRTNIMPFNNRAWL-VLISTL-VICGTFLY--FMKYVSYRLR--YSGTQV 416
            .::||...| ...|...:.:.|.:...|: ||::.| |.|..|:.  |..|..|...  ...:.|
  Rat   552 GISILYRKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLFVIARFTPYEWYNPHPCNPDSDV 616

  Fly   417 KFHHSRKLEKSMLDIFALFIQQPSAPLSFDRFAPR------------FFLATI-------LCATI 462
            ..::...|......:.|| :||.|      ...|:            ||...|       |.|.:
  Rat   617 VENNFTLLNSFWFGVGAL-MQQGS------ELMPKALSTRIVGGIWWFFTLIIISSYTANLAAFL 674

  Fly   463 TLENIYS----------------GQLK--SMLTFPFYSAPVDTIEK-WA-QSGWKWSAPSIIWVH 507
            |:|.:.|                |.::  |.:|| |..:.:.|.|| || .|..:.||
  Rat   675 TVERMESPIDSADDLAKQTKIEYGAVRDGSTMTF-FKKSKISTYEKMWAFMSSRQQSA------- 731

  Fly   508 TVQSSDLETEQILARNFEVHDYSYLSNVSFMPNYGFGIERLSSGSLSVGDYVSTEALENRIVLHD 572
            .|::||...:::|..     ||:.|               :.|.|:   :||:.
  Rat   732 LVKNSDEGIQRVLTT-----DYALL---------------MESTSI---EYVTQ----------- 762

  Fly   573 DLYFDYTRAVSIRGWILMPELNKHIRTCQET---GLYFHWELEFIDK------------YMDKKK 622
                                     |.|..|   ||        ||.            |.||..
  Rat   763 -------------------------RNCNLTQIGGL--------IDSKGYGVGTPIGSPYRDKIT 794

  Fly   623 QEVLMDLANG--HKVK-------GAPQ-------ALDVRNIAGALFVLAFGVAFAGCALVAELL 670
            ..:|.....|  |.:|       |.|:       ||.|.||.|...|||.|:..:....:.|.|
  Rat   795 IAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAIGEFL 858

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.