Protein Alignment Ir92a and GRID2

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_011530195.2
• Gene: GRID2 / 2895
• HGNCID: 4576
• Length: 1035
• Species: Homo sapiens
• Alignment Length: 775
• Identity: 136/775 - (17%)
• Similarity: 286/775 - (36%)
• Gaps: 180/775 - (23%)

  Fly     5 PLVMHLSQLLRIIVGQYFAEFPSILIVYNNSASTTPLQLEYL-----SALELVLRELSKPIRLQW 64
            |:.:| ..:||::....:.:|   :|.|::......:| |:|     ..:::.|:::...|. :.
Human   161 PVYLH-DVILRVVTEYAWQKF---IIFYDSEYDIRGIQ-EFLDKVSQQGMDVALQKVENNIN-KM 219

  Fly    65 INVAF----LKDLNDLEDQVMGA---LNSSVTEGFITILSQTHHFIHARYYATRNANV------- 115
            |...|    :::||...|.:..|   :|.:..:.|||.:.:|:......::...|..:
Human   220 ITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQE 284

  Fly   116 -------RLKDKRYLF--------------------LCEDESP-AELLCMDILQFYPHHLMV--- 149
                   ||...|..|                    ||:.:.| |:.:.:..|..|...|::
Human   285 LVRRSIGRLTIIRQTFPVPQNISQRCFRGNHRISSTLCDPKDPFAQNMEISNLYIYDTVLLLANA 349

  Fly   150 -------RPGTETAPTGPTGPHPDPRRG----------GGASVSTKNKDDGEGGAGNKTTSPYRD 197
                   |.....|.......:..|.:|          ||.|..|...:.||.| ||.      :
Human   350 FHKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKGGVSGLTGELEFGENG-GNP------N 407

  Fly   198 INFE----------------------------LWTQKFVGA---VGNLDALLLDAFLPNETFANR 231
            ::||                            :|.|  :|.   |..|:..|.|..|.|
Human   408 VHFEILGTNYGEELGRGVRKNERIRPQGSTGKIWPQ--LGCWNPVTGLNGSLTDKKLEN------ 464

  Fly   232 VELYPNKLLNLQRRSLLVGSITYVPYTITNYVPAGQGDVDPIHPQWPNRSLTFDGAEANVMKTFC 296
                     |::...|.|.::...|:.:.:....|:          |.:   :.|...:|:....
Human   465 ---------NMRGVVLRVVTVLEEPFVMVSENVLGK----------PKK---YQGFSIDVLDALS 507

  Fly   297 QVHNCHLRVEAYGADNWGGIYDNESSDGMLGDIYEQRVEMAIGCIYNWYD--GITETSHTIARSS 359
            .....:..:.......:|...::.:.:|::|::..:|.::.|..:....|  .:.:.:......|
Human   508 NYLGFNYEIYVAPDHKYGSPQEDGTWNGLVGELVFKRADIGISALTITPDRENVVDFTTRYMDYS 572

  Fly   360 VTILGPAPAPLPSWRTNIMPFNNRAWLVLISTLVICGTFLYFMKYVSYRLRYSGTQVKFHHSRKL 424
            |.:|.............:.||:...|..:..|:::.|..:|.:.:::......|:..    |..|
Human   573 VGVLLRRAEKTVDMFACLAPFDLSLWACIAGTVLLVGLLVYLLNWLNPPRLQMGSMT----STTL 633

  Fly   425 EKSMLDIFALFIQQPSAPLSFDRFAPRFFL-ATILCATITLENIYSGQLKSMLTFPFYSAPVDTI 488
            ..||..::..|:|| ...:.:...|.|..: |..|.|.|.:.: |:..|.:.||.....:.:.::
Human   634 YNSMWFVYGSFVQQ-GGEVPYTTLATRMMMGAWWLFALIVISS-YTANLAAFLTITRIESSIQSL 696

  Fly   489 E---KWAQSGWKWSAPSIIWVHTVQS--SDLETEQILARNFEVHDYSYLSNVSFMPNYGFGIERL 548
            :   |..:..:.....|.::.|....  :..|.:.:.::.:.:.:.|..|..:.:.:.. ||:::
Human   697 QDLSKQTEIPYGTVLDSAVYEHVRMKGLNPFERDSMYSQMWRMINRSNGSENNVLESQA-GIQKV 760

  Fly   549 SSGSLSVGDYVSTEALENRIVLHD-DLYFDYT--RAVSIRGWILMPE--------LNKHIRTCQE 602
            ..|:.:   :|...|:...:.::| |..| ||  ..|:.||:.:..:        .::.|...|:
Human   761 KYGNYA---FVWDAAVLEYVAINDPDCSF-YTIGNTVADRGYGIALQHGSPYRDVFSQRILELQQ 821

  Fly   603 TGLYFHWELEFI-DKYMDKKKQEVLMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFA 661
            .|     :::.: .|:..|..|   .||.:....|....|||:::.||...:||.|:..:
Human   822 NG-----DMDILKHKWWPKNGQ---CDLYSSVDTKQKGGALDIKSFAGVFCILAAGIVLS 873

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156077
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840