DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ir92a and Grik5

DIOPT Version :9

Sequence 1:	NP_001097845.2	Gene:	Ir92a / 42415	FlyBaseID:	FBgn0038789	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	XP_006228444.1	Gene:	Grik5 / 24407	RGDID:	2735	Length:	980	Species:	Rattus norvegicus

Alignment Length:	505	Identity:	102/505 - (20%)
Similarity:	175/505 - (34%)	Gaps:	129/505 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 NETFA-NRVELYPNKLLNLQRRSLLVGSITYVPYTITNYVPAGQGDVDPIHPQWPN-RSLT---- 283
            |.|.| |...|..|....|..::|:|.:|...||.:..                || ::|:
  Rat   394 NRTLAMNATTLDINLSQTLANKTLVVTTILENPYVMRR----------------PNFQALSGNER 442

  Fly   284 FDGAEANVMKTFCQVHNCHLRVEAYGADNWGGIYDNESSDGMLGD-IYEQRVEMAIGC--IYNWY 345
            |:|...::::...::.....|:.......:|....|.|..||:|: |..|:.::|:..  |....
  Rat   443 FEGFCVDMLRELAELLRFRYRLRLVEDGLYGAPEPNGSWTGMVGELINRQKADLAVAAFTITAER 507

  Fly   346 DGITETSHTIARSSVTIL-----GPAPAPLPSWRTNIMPFNNRAWL-VLISTLVI-CGTFL---- 399
            :.:.:.|.......::||     |..    |.:.:.:.||:...|| :|::.|.: |..||
  Rat   508 EKVIDFSKPFMTLGISILYRVHMGRK----PGYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARL 568

  Fly   400 ----YFMKYVSYRLRYSGTQVKFHHSRKLEKSMLDIFALFIQQPSAPLSFDRFAPRFFLATILCA 460
                ::..:...|.|....:.::    .|..|:......|:||.|      ...||......:..
  Rat   569 SPYEWYNPHPCLRARPHILENQY----TLGNSLWFPVGGFMQQGS------EIMPRALSTRCVSG 623

  Fly   461 -----TITLENIYSGQLKSMLTFPFYSAPVDTIEKWA---------------------------Q 493
                 |:.:.:.|:..|.:.||......||::.:..|                           |
  Rat   624 VWWAFTLIIISSYTANLAAFLTVQRMEVPVESADDLADQTNIEYGTIHAGSTMTFFQNSRYQTYQ 688

  Fly   494 SGWKW---SAPSIIWVHTVQSSDLETEQILARNFEVHDYSYLSNVSFMPNYGFGIERLSSGSLSV 555
            ..|.:   ..||:.    |:|    ||:.:||..... |::|.. |.|..|.   .||:.....:
  Rat   689 RMWNYMQSKQPSVF----VKS----TEEGIARVLNSR-YAFLLE-STMNEYH---RRLNCNLTQI 740

  Fly   556 GDYVSTEALENRIVLHDDLYFDYTRAVSIRGWILMPELNKHIRTCQETGLYFHWELEFIDKYMDK 620
            |..:.|:.....:.|......:.|.|      ||..:.|..:...:..    .||.....|..|
  Rat   741 GGLLDTKGYGIGMPLGSPFRDEITLA------ILQLQENNRLEILKRK----WWEGGRCPKEED- 794

  Fly   621 KKQEVLMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALVAELL 670
                        |:.||    |.:.||.|...||..|:..|....|.|.:
  Rat   795 ------------HRAKG----LGMENIGGIFVVLICGLIIAVFVAVMEFI 828

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	3/6 (50%)
Grik5	XP_006228444.1	Periplasmic_Binding_Protein_Type_2	414..785	CDD:389745	78/423 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350158
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840