Protein Alignment Ir92a and Grin2d

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 851
• Identity: 165/851 - (19%)
• Similarity: 276/851 - (32%)
• Gaps: 275/851 - (32%)

  Fly    17 IVGQYFAEFPSILIV----YNNSASTTPLQL-----EYLSALELVLRELSKPIRLQWINV----- 67
            :.|::|..:|..:..    :.....:|.|||     :.|..:..||.|      ..|.:.
Mouse   136 VSGRWFRSWPPAISPKEQGHEKEKGSTFLQLGSSTEQQLQVIFEVLEE------YDWTSFVAVTT 194

  Fly    68 ------AFLKDLNDLEDQVMGALNSSVTEGFITILSQTHHFIHARYYATRNANVRLKDKRYLFLC 126
                  |||..:..|.|   |:|......|.:|:.......:......:.:|.:||     ||..
Mouse   195 RAPGHRAFLSYIEVLTD---GSLVGWEHRGALTLDPGAGEAVLGAQLRSVSAQIRL-----LFCA 251

  Fly   127 EDESPAELLCMDILQFYPHHLMVRPGTETAPTGP------TGPHPDPRRGGGASVSTKNKDDGE- 184
            .:|:..               :.|...|...|||      .|  |....|||:.|      .||
Mouse   252 REEAEP---------------VFRAAEEAGLTGPGYVWFMVG--PQLAGGGGSGV------PGEP 293

  Fly   185 ----GGAGNKT------TSPYRDINFELWTQKFVG---AVGNLDALLLD-AFLP----------- 224
                |||....      ::.:||   :|..:...|   ......|||.| .|||
Mouse   294 LLLPGGAPLPAGLFAVRSAGWRD---DLARRVAAGVAVVARGAQALLRDYGFLPELGHDCRAQNR 355

  Fly   225 ------------NETFANR----------------------------VELYPNKLLNLQ------ 243
                        |.|:.||                            |..:..:.|.|:
Mouse   356 THRGESLHRYFMNITWDNRDYSFNEDGFLVNPSLVVISLTRDRTWEVVGSWEQQTLRLKYPLWSR 420

  Fly   244 ----------RRSLLVGSITYVPYTITNYVPAGQGDVDPI------------------HPQWPNR 280
                      .:.|.|.::...|:.|..  ||     |||                  |.....|
Mouse   421 YGRFLQPVDDTQHLTVATLEERPFVIVE--PA-----DPISGTCIRDSVPCRSQLNRTHSLVAPR 478

  Fly   281 SLTFDG--AEANVMKTFC------QVHNCHLRVEAYGADNW------GGIYDNESSDGMLGDIYE 331
            |...|.  .|....|.||      ..|......:.|...|.      .|::     :||:|:::.
Mouse   479 SPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTNGKHGKKIDGVW-----NGMIGEVFY 538

  Fly   332 QRVEMAIGC---------IYNWYDGITET--SHTIARSSVTILGPAPAPLPSWRTNIM---PFNN 382
            ||.:||||.         |.::.....||  |..:|||:.|: .|:.....:|....|   |::.
Mouse   539 QRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTV-SPSAFLAFAWLMPPMSPEPYSP 602

  Fly   383 RAWL---VLISTLVICGTFLY-FMKYVSYRLRYSGTQVKFHHSRKLEKSMLDIFALF------IQ 437
            ..|:   |:..|:|....|:: ::..|.|....:..:.....:..:.||:..::||.      ::
Mouse   603 AVWVMMFVMCLTVVAVTVFIFEYLSPVGYNRSLATGKRPGGSTFTIGKSIWLLWALVFNNSVPVE 667

  Fly   438 QPSAPLSFDRFAPRFFLATILCATITLENIYSGQLKSMLTFPFYSAPVDTIEKWAQSGWKWSAPS 502
            .|....|........|.|.|..|:.|         .::..|......|||:.  ..|..|:..|.
Mouse   668 NPRGTTSKIMVLVWAFFAVIFLASYT---------ANLAAFMIQEEYVDTVS--GLSDRKFQRPQ 721

  Fly   503 ----IIWVHTVQSSDLETEQILARNF-EVHDYSYLSNVSFMPNYGFGIERLSSGSLSVGDYVSTE 562
                .:...||.:.  .||:.:..|: ::|.|....|   .|.....:.:|.:|.|..  ::...
Mouse   722 EQYPPLKFGTVPNG--STEKNIRSNYPDMHSYMVRYN---QPRVEEALTQLKAGKLDA--FIYDA 779

  Fly   563 ALENRIVLHDDLYFDYTRAVSIRGWILMPELNKHIRTCQETGLYFH----WE-------LEFI-D 615
            |:.|.:...|:            |..|:...:..:......|:..|    |:       |:|: |
Mouse   780 AVLNYMARKDE------------GCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGD 832

  Fly   616 KYMDKKKQEVLMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGCALVAELLI--------- 671
            ..::..::..|..:.:..|::.....||:.|:||..::|...:..:......|.|:
Mouse   833 DEIEMLERLWLSGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRHCLG 897

  Fly   672 --HRMD 675
              ||||
Mouse   898 PTHRMD 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:415822	58/298 (19%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	91/459 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846594
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930