Protein Alignment Ir92a and Grin2c

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 617
• Identity: 128/617 - (20%)
• Similarity: 226/617 - (36%)
• Gaps: 133/617 - (21%)

  Fly   139 ILQFYPHHLMVRPGTETAPTGPTGPHPDPRRGGG-------ASVSTKNKD--DGEGGAGNKTTSP 194
            ||....|....:.||..||.|....||.|.....       .:|:.:.:|  ...||...:.|..
Mouse   357 ILALGAHSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPGGYLVQPTMV 421

  Fly   195 YRDIN-FELWTQKFVGAVGNLDALLLDAFLPNETFANRVELYPNKLLNLQ----RRSLLVGSITY 254
            ...:| ..||..     ||..|..:|....|         ::|....:||    .|.|.|.::..
Mouse   422 VIALNRHRLWEM-----VGRWDHGVLYMKYP---------VWPRYSTSLQPVVDSRHLTVATLEE 472

  Fly   255 VPYTIT------------NYVPA--------GQGDVDPIHPQWPNRSLTFDGAEANVMKTFCQV- 298
            .|:.|.            |.||.        ..||:.|.      ..|...|...:::|...:|
Mouse   473 RPFVIVESPDPGTGGCVPNTVPCRRQSNHTFSSGDITPY------TKLCCKGFCIDILKKLAKVV 531

  Fly   299 ---HNCHLRVEAYGADNWGGIYDNESSDGMLGDIYEQRVEMAIGC---------IYNWYDGITET 351
               ::.:|...........|::     :||:|::|.:|.:||||.         |.::.....||
Mouse   532 KFSYDLYLVTNGKHGKRVRGVW-----NGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVET 591

  Fly   352 --SHTIARSSVTILGPAPAPLPSWRTNIMPFNNRAWL---VLISTLVICGTFLY-FMKYVSYRLR 410
              |..:|||:.|:   :|:..      :.|::...|:   |:..|:|....|:: :...|||...
Mouse   592 GISVMVARSNGTV---SPSAF------LEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQN 647

  Fly   411 YSGTQVKFHHSRKLEKSMLDIFALF------IQQPSAPLSFDRFAPRFFLATILCATITLENIYS 469
            .:..:.....|..:.||:..::||.      |:.|....|........|.|.|..|:.|
Mouse   648 LTKGKKSGGPSFTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYT------ 706

  Fly   470 GQLKSMLTFPFYSAPVDTIEKWAQSGWKWSAPSIIW----VHTVQSSDLETEQILARNF-EVHDY 529
               .::..|......:||:.  ..|..|:..|...:    ..||.:.  .||:.:..|: ::|.:
Mouse   707 ---ANLAAFMIQEQYIDTVS--GLSDKKFQRPQDQYPPFRFGTVPNG--STERNIRSNYRDMHTH 764

  Fly   530 SYLSNVSFMPNYGFGIERLSSG----SLSVGDYVSTEALENRIVLHDD----LYFDYTRAVSIRG 586
            ....|...:.:   .:..|..|    |..:..::...|:.|.:...|:    :.....:..:..|
Mouse   765 MVKFNQRSVED---ALTSLKMGARHVSRKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTG 826

  Fly   587 WILMPELNKHIRTCQETGLYFHWELEFIDKYMDKKKQEV-LMDLANGHKVKGAPQALDVRNIAGA 650
            :.:..:.:.|.:...:..|     |:|:.....:|.:.| |..:.:..|.:.....||:.|:||.
Mouse   827 YGIAMQKDSHWKRAIDLAL-----LQFLGDGETQKLETVWLSGICHNEKNEVMSSKLDIDNMAGV 886

  Fly   651 LFVL--AFGVA---FAGCALVAELLIHRMDLS 677
            .::|  |.|:|   ||...||...|.|.:..|
Mouse   887 FYMLLVAMGLALLVFAWEHLVYWKLRHSVPSS 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	23/93 (25%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	84/446 (19%)
		NMDAR2_C	905..>980	CDD:371139	5/14 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846622
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840