Protein Alignment Ir92a and Grik3

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001074566.1
• Gene: Grik3 / 14807
• MGIID: 95816
• Length: 919
• Species: Mus musculus
• Alignment Length: 795
• Identity: 155/795 - (19%)
• Similarity: 271/795 - (34%)
• Gaps: 236/795 - (29%)

  Fly     3 LQPLVMHLSQLLRIIVGQYFAEFPSILIVYNNSASTTPLQLEYLSA-----LELVLREL------ 56
            |...::.|.|.|:         :.|..:||::|.....|| |.:.|     :.|.:|:|
Mouse   159 LSHAILDLVQSLK---------WRSATVVYDDSTGLIRLQ-ELIMAPSRYNIRLKIRQLPIDSDD 213

  Fly    57 SKPIRLQWINVAFLKDLNDLED--------QVMGA--LNSSVTEGFITILSQTHHFIHAR--YYA 109
            |:|:         ||::....:        ..|.|  |..::..|.:|   :.:|||...  .||
Mouse   214 SRPL---------LKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMT---EYYHFIFTTLDLYA 266

  Fly   110 T-----RNANVRLKDKRYLFLCEDESP-----AELLCMDILQFYPH------------------- 145
            .     |.:.|.|...|.|.:   ::|     .|...|:.||..|.
Mouse   267 LDLEPYRYSGVNLTGFRILNV---DNPHVSAIVEKWAMERLQAAPRAESGLLDGVMMTDAALLYD 328

  Fly   146 --HLMVRPGTETAPTGPTGPHPDPR----RGGGASVSTKNKDDGEGGAG----NKTTSPYRDINF 200
              |: |....:.||..........|    |.||..::...:...||..|    |||:....|.:.
Mouse   329 AVHI-VSVCYQRAPQMTVNSLQCHRHKAWRFGGRFMNFIKEAQWEGLTGRIVFNKTSGLRTDFDL 392

  Fly   201 ELWTQK-----FVGAVGNLDALLLDAFLPNETFANRVELYPNKLLNLQRRSLLVGSITYVPYTIT 260
            ::.:.|     .||.....|.|.:     .|....|   .||...:|..|||:|.::...|:.:.
Mouse   393 DIISLKEDGLEKVGVWSPADGLNI-----TEVAKGR---GPNVTDSLTNRSLIVTTVLEEPFVMF 449

  Fly   261 NYVPAGQGDVDPIHPQWPNRSL----TFDGAEANVMKTFCQVHNCHLRVEAYGADNWGGIYDNES 321
                           :..:|:|    .|:|...:::|....:......:.......:|...|...
Mouse   450 ---------------RKSDRTLYGNDRFEGYCIDLLKELAHILGFSYEIRLVEDGKYGAQDDKGQ 499

  Fly   322 SDGMLGDIYEQRVEMAIG--CIYNWYDGITETSHTIARSSVTILGPAP-APLPSWRTNIMPFNNR 383
            .:||:.::.:.:.::|:.  .|.:..:...:.|.......|:||...| ...||..:.:.|.:..
Mouse   500 WNGMVKELIDHKADLAVAPLTITHVREKAIDFSKPFMTLGVSILYRKPNGTNPSVFSFLNPLSPD 564

  Fly   384 AWL-VLISTL-VICGTFLY--FMKYVSYRLR--YSGTQVKFHHSRKLEKSMLDIFALFIQQPSAP 442
            .|: ||::.| |.|..|:.  |..|..|...  ..|::|..::...|......:.:| :||.|
Mouse   565 IWMYVLLAYLGVSCVLFVIARFSPYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSL-MQQGS-- 626

  Fly   443 LSFDRFAPR------------FFLATI-------LCATITLENIYS----------------GQL 472
                ...|:            ||...|       |.|.:|:|.:.|                |.:
Mouse   627 ----ELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAV 687

  Fly   473 KSMLTFPFY-SAPVDTIEK-WAQSGWKWSAPSIIWVHTVQSSDLETEQILARNFEVHDYSYL--- 532
            |...|..|: .:.:.|.|| ||   :..|.||.:    |::::...::.|..     ||:.|
Mouse   688 KDGATMTFFKKSKISTFEKMWA---FMSSKPSAL----VKNNEEGIQRTLTA-----DYALLMES 740

  Fly   533 SNVSFMPNYGFGIERLSSGSLSVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGWILMPELNKHI 597
            :.:.::......:.::.....|.|..:.|           .:...|...::|....|..|...||
Mouse   741 TTIEYITQRNCNLTQIGGLIDSKGYGIGT-----------PMGSPYRDKITIAILQLQEEDKLHI 794

  Fly   598 RTCQETGLYFHWELEFIDKYMDKKKQEVLMDLANGHKVKGAPQ-------ALDVRNIAGALFVLA 655
            .                     |:|         ..:..|.|:       ||.::.|.|...|||
Mouse   795 M---------------------KEK---------WWRGSGCPEEENKEASALGIQKIGGIFIVLA 829

  Fly   656 FGVAFAGCALVAELL 670
            .|:..:....|.|.:
Mouse   830 AGLVLSVLVAVGEFI 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Grik3	NP_001074566.1	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388	60/288 (21%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	78/442 (18%)
		Glutamate binding. /evidence=ECO:0000250	690..692		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846608
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840