Protein Alignment Ir92a and Grid1

DIOPT Version :10

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_032192.2
• Gene: Grid1 / 14803
• MGIID: 95812
• Length: 1009
• Species: Mus musculus
• Alignment Length: 659
• Identity: 117/659 - (17%)
• Similarity: 215/659 - (32%)
• Gaps: 196/659 - (29%)

  Fly    90 EGFITILSQTHHFIHARYYATRNA-NVRLKDKRYLFLCEDESPAELLCMDILQFYPHHLMVRPGT 153
            ||::.:|..::.:::.......|| :.:|:|:::      .|.|.|.|            :|..|
Mouse   310 EGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKW------HSMASLNC------------IRKST 356

  Fly   154 ETAPTGPTGPHPDPRRGGGASVSTKNKDDGEGGAG-----NKTTSPYRDINFELWTQKFVGAVGN 213
            :            |..||.:.:.|..|....|..|     ..:::||  :.||:....:
Mouse   357 K------------PWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPY--VQFEILGTTY------ 401

  Fly   214 LDALLLDAFLPNETFANRVELY----PNKLLN-----------LQRRSLLVGSITYVPYTITNYV 263
                       :|||...:...    ..|.||           ||..:|.|.::...|:.:....
Mouse   402 -----------SETFGKDMRKLATWDSEKGLNGSLQERPMGSRLQGLTLKVVTVLEEPFVMVAEN 455

  Fly   264 PAGQGDVDPIHPQWPNRSLTFDGAEANVMKTFCQVHNCHLRVEAYGADN--WGGIYDNESSDGML 326
            ..||          |.|   :.|...:|:....:.  ...:.|.|.|.:  :|....|.|.:||:
Mouse   456 ILGQ----------PKR---YKGFSIDVLDALAKA--LGFKYEIYQAPDGRYGHQLHNTSWNGMI 505

  Fly   327 GDIYEQRVEMAIGC--IYNWYDGITETSHTIARSSVTILGPAPAPLPSWRTNIMPFNNRAWLVLI 389
            |::..:|.::||..  |....:.:.:.|......||.||...|....|..:...||:...|..:.
Mouse   506 GELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKPEEKISIFSLFAPFDFAVWACIA 570

  Fly   390 STLVICGTFLYFMKYVSYRLRYSGTQVKFHHSRKLEKSMLDIFALFIQQPSAPLSFDRFAPRFFL 454
            :.:.:.|..::.:..:......|.||.:...|..|..::..::..|:|| ....|.:..|.|..:
Mouse   571 AAIPVVGVLIFVLNRIQAVRSQSATQPRPSASATLHSAIWIVYGAFVQQ-GGESSVNSVAMRIVM 634

  Fly   455 ATILCATITLENIYSGQLKSMLTFPFYSAPVDTIEKWAQSGWKWSAPSIIWVHTVQSSDLETEQI 519
            .:....|:.:.:.|:..|.:.||......|:.|.:.                   .|..||....
Mouse   635 GSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQD-------------------LSKQLEMSYG 680

  Fly   520 LARNFEVHDYSYLSNVSFMPNYGFGIERLSSGSLSVGDYVSTEALENRIVLHDDLYFDYTRAVSI 584
            ..|:..|::|....                          .|..||     .|..:.:..|.:|.
Mouse   681 TVRDSAVYEYFRAK--------------------------GTNPLE-----QDSTFAELWRTISK 714

  Fly   585 RGWI--LMPELNKHIRTCQETGLYFHWELEFID-------------------------------K 616
            .|..  .:...::.||..::....|.|::..::                               .
Mouse   715 NGGADNCVSNPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSP 779

  Fly   617 YMDKKKQEVL---------------------MDLANGHKVKGAPQALDVRNIAGALFVLAFGVAF 660
            |.|...|.:|                     .||.:....:...::|.:.:.||...:||.|:..
Mouse   780 YRDLFSQRILELQDTGDLDVLKQKWWPHTGRCDLTSHSSTQTEGKSLKLHSFAGVFCILAIGLLL 844

  Fly   661 AGCALVAEL 669
            |  .|||.|
Mouse   845 A--CLVAAL 851

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Grid1	NP_032192.2	Interaction with CBLN1. /evidence=ECO:0000269|PubMed:27418511	21..436		31/174 (18%)
		PBP1_iGluR_delta_1	25..425	CDD:380615	30/163 (18%)
		PBP2_iGluR_delta_1	436..806	CDD:270448	72/435 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..960