Protein Alignment Ir92a and Gria4

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_006509904.1
• Gene: Gria4 / 14802
• MGIID: 95811
• Length: 912
• Species: Mus musculus
• Alignment Length: 600
• Identity: 110/600 - (18%)
• Similarity: 207/600 - (34%)
• Gaps: 186/600 - (31%)

  Fly   157 PTGPTGPHPDPRRGGGASVSTKNKDDGEGGAGNKTTSPY-RDIN-----FELWT--QKFVGAVGN 213
            |..|.|...|..|       |..:...:|..||.....| |.:|     |||.:  .:.||...:
Mouse   335 PAAPWGQGIDMER-------TLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWND 392

  Fly   214 LDALLL--DA-FLPNETFANRVELYPNKLLNLQRRSLLVGSITYVPYTITNYVPAGQGDVDPIHP 275
            :|.|:|  || .|.|:|.|            ::.|:::|.:|...||.:
Mouse   393 MDKLVLIQDAPTLGNDTAA------------IENRTVVVTTIMESPYVM---------------- 429

  Fly   276 QWPNRSLTFDGAE----------ANVMKTFCQVHNCHLRVE---------AYGADNWGGIYDNES 321
             :......|:|.:          :.:.|        |:.::         .|||.:    .|.:.
Mouse   430 -YKKNHEMFEGNDKYEGYCVDLASEIAK--------HIGIKYKIAIVPDGKYGARD----ADTKI 481

  Fly   322 SDGMLGDIYEQRVEMAIGCIYNWYDGITETSHTIARSSVTILGPAPAPLPSWRTNIM-------- 378
            .:||:|::...:.|:||..:          :.|:.|..|....   .|..|...:||
Mouse   482 WNGMVGELVYGKAEIAIAPL----------TITLVREEVIDFS---KPFMSLGISIMIKKPQKSK 533

  Fly   379 --------PFNNRAWLVLISTLVICGTFLYFMKYVSYRLRYSGTQVKFHHSRKLE---------- 425
                    |.....|:.::...:.....|:.:.      |:|..:   .|:.:.|
Mouse   534 PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVS------RFSPYE---WHTEEPEDGKEGPSDQP 589

  Fly   426 -------KSMLDIFALFIQQPSAPLSFDRFAPRFFLATILCA-----TITLENIYSGQLKSMLTF 478
                   .|:......|:||..      ..:||.....|:..     |:.:.:.|:..|.:.||.
Mouse   590 PNEFGIFNSLWFSLGAFMQQGC------DISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTV 648

  Fly   479 PFYSAPVDTIEKWAQSGWKWSAPSIIWVHTVQSSDLETEQILARN-FEVHD--YSYLSNVS---F 537
            ....:|:::.|..|:.       :.|...|:.|.  .|::...|: ..|::  ::|:.:..   |
Mouse   649 ERMVSPIESAEDLAKQ-------TEIAYGTLDSG--STKEFFRRSKIAVYEKMWTYMRSAEPSVF 704

  Fly   538 MPNYGFGIERL--SSGSL------SVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGWILMPELN 594
            ......|:.|:  |.|..      ::.:|:......:.:.:..:|........:.:|..|...:|
Mouse   705 TRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSSLRTPVN 769

  Fly   595 KHIRTCQETGLYFHWELEFIDKYMDKKKQEVLMDLAN-GHKVKGA---PQALDVRNIAGALFVLA 655
            ..:....|.|:            :||.|.:...|... |.|..|:   ..||.:.|:||..::|.
Mouse   770 LAVLKLSEAGV------------LDKLKNKWWYDKGECGPKDSGSKDKTSALSLSNVAGVFYILV 822

  Fly   656 FGVAFAGCALVAELL 670
            .|:   |.|::..|:
Mouse   823 GGL---GLAMLVALI 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
Gria4	XP_006509904.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	20/71 (28%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	71/458 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846601
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840