Protein Alignment Ir92a and grin2cb

DIOPT Version :9

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_009305071.2
• Gene: grin2cb / 100333648
• ZFINID: ZDB-GENE-100308-2
• Length: 1328
• Species: Danio rerio
• Alignment Length: 827
• Identity: 147/827 - (17%)
• Similarity: 275/827 - (33%)
• Gaps: 240/827 - (29%)

  Fly    10 LSQLLRIIVGQYFAEFP-------SILIVYNNSASTTPLQL-----EYLSALELVLRELSKPIRL 62
            ::|:|..:..|  ...|       |.:::.:.:..:|.||:     :.::|:..|:.|.:
Zfish   112 VAQILDFVSSQ--TSIPIVGISGGSAVVIPHKADGSTFLQMGASIDQQINAMFKVMEEYN----- 169

  Fly    63 QWINVAFLKDLNDLEDQVMGALNSSVTEGFITILSQTHHFIHARYY------------------- 108
             |.|...:               :|:..|:.|.:.....|....|:
Zfish   170 -WGNFVVI---------------TSLYPGYETFVDYIRSFTDTSYFLWELQDVLSFEMSVGANDI 218

  Fly   109 ATRNANVRLKDKRYLFLCEDESPAELLCM--DILQFYPHHLMVRP-----GTETAPTG--PTG-- 162
            .||....::..:.||..|..|....|..|  |:....|.::.:.|     ..|.||..  |.|
Zfish   219 RTRRLLQQVDSQVYLVYCSHEEAQYLFRMASDVGLLGPGYIWIVPSLAVGNPEAAPPASFPVGVI 283

  Fly   163 --------PHPDPRRGGGASVSTK-----NKDDG---EGGAGNKTTSP---------YRDINFEL 202
                    .....|...|.::..|     :|..|   ||  .:..:||         :|.:....
Zfish   284 SIITDRWRKTLRQRVREGVAIIVKGVHSFHKHRGFIPEG--HSDCSSPVKSYANNSLFRHMLNVS 346

  Fly   203 WTQKFVGAVGNLDALLLD-----AFLPNETFANRVELYPNKLLNLQ----------------RRS 246
            |..|.:..  |.|..|.:     ..|..|...::|..|...:|.::                .|.
Zfish   347 WEHKDLSF--NSDGYLTNPSMVIIALDRENHWDKVGSYEGGILQMRYPVWPRYGSFLEPVSDNRH 409

  Fly   247 LLVGSITYVPYTITNYVPAGQG----DVDPIHPQWPNRSLTFDGAEANVMKTFCQ---------- 297
            |.|.::...|:.|...|....|    :..|...| .||:.:..|......|..|:
Zfish   410 LTVATLEERPFVIVESVDPATGTCVRNTVPCRRQ-SNRTESIIGHTEPYTKLCCKGFCIDILKKL 473

  Fly   298 ------VHNCHLRVEAYGADNWGGIYDNESSDGMLGDIYEQRVEMAIGC---------IYNWYDG 347
                  .::.:|...........|::     :||:|:::.:|.:||||.         |.::...
Zfish   474 SRTIKFSYDLYLVTNGKHGKMVRGVW-----NGMIGEVFYKRADMAIGSLTINEERSEIVDFSVP 533

  Fly   348 ITET--SHTIARSSVTILGPAPAPLPSWRTNIMPFNNRAWL---VLISTLVICGTFLY-FMKYVS 406
            ..||  |..:|||:.|:   :|:..      :.|::...|:   |:..|:|....|:: :...|.
Zfish   534 FVETGISVMVARSNGTV---SPSAF------LEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVG 589

  Fly   407 YRLRYSGTQVKFHHSRKLEKSMLDIFALF------IQQPSAPLSFDRFAPRFFLATILCATITLE 465
            |.......:.....:..:.||:..::.:.      |:.|....|........|.|.|..|:.|
Zfish   590 YNRSLVSAKAPGGPTFTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYT-- 652

  Fly   466 NIYSGQLKSMLTFPFYSAPVDTIEKWAQSGWKWSAPSIIWVH-------TVQSSDLETEQILARN 523
                   .::..|......:||:.  ..|..|:..|.   .|       ||.:.  .||:.:..|
Zfish   653 -------ANLAAFMIQEQYIDTVS--GLSDKKFQKPQ---EHYPPFRFGTVPNG--STERNIRSN 703

  Fly   524 F-EVHDYSYLSNVSFMPNYGFGIER----LSSGSLSVGDYVSTEALENRIVLHDD----LYFDYT 579
            : ::|.:....|..       |:|.    |.:|.|..  ::...|:.|.:...|:    :.....
Zfish   704 YPDMHTHMIKYNQK-------GVEEALNSLKTGKLDA--FIYDAAVLNYMAGKDEGCKLVTIGSG 759

  Fly   580 RAVSIRGWILMPELNKHIRTCQETGLYFHWE-------LEFIDKYMDKKKQEV-LMDLANGHKVK 636
            :..:..|:.:  .|.|..|          |:       |:|:.....::.:.| |..:....|.:
Zfish   760 KVFATTGYGI--ALQKDSR----------WKRPIDLALLQFLGDGDTQRLETVWLSGICQNEKNE 812

  Fly   637 GAPQALDVRNIAGALFVLAFGVAFAGCALVAELL--------IHRMD 675
            .....||:.|:||..::|...:..:......|.|        :|:.|
Zfish   813 VMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVHKSD 859

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
grin2cb	XP_009305071.2	PBP1_iGluR_NMDA_NR2	37..396	CDD:107373	54/310 (17%)
		PBP2_iGluR_NMDA_Nr2	407..808	CDD:270436	82/452 (18%)
		NMDAR2_C	845..>932	CDD:313729	3/15 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591719
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930