Protein Alignment Ir92a and grin2ca

DIOPT Version :10

• Sequence 1: NP_001097845.2
• Gene: Ir92a / 42415
• FlyBaseID: FBgn0038789
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001352716.1
• Gene: grin2ca / 100003342
• ZFINID: ZDB-GENE-070822-3
• Length: 1400
• Species: Danio rerio
• Alignment Length: 529
• Identity: 105/529 - (19%)
• Similarity: 190/529 - (35%)
• Gaps: 126/529 - (23%)

  Fly   211 VGNLDALLLDAFLP----NETFANRVELYPNKLLNLQRRSLLVGSITYVPYTITNYVPAGQG--- 268
            |||.::.:|....|    ..||...|.         ..|.|.|.::...|:.|...|....|
Zfish   381 VGNYESGILQMRYPVWPRYGTFLEPVS---------DNRHLTVATLEERPFVIVEAVDPVTGTCL 436

  Fly   269 -DVDPIHPQWPNRSLTFDGAEANVMKTFCQ----------VHNCHLRVEAYGADNW------GGI 316
             :..|...| .|::.|..|......|..|:          ..|.....:.|...|.      .||
Zfish   437 SNTVPCRRQ-SNKTETIVGHTEPYTKLCCKGFCIDILKKLSRNIKFSYDLYLVTNGKHGKLVRGI 500

  Fly   317 YDNESSDGMLGDIYEQRVEMAIGC---------IYNWYDGITET--SHTIARSSVTILGPAPAPL 370
            :     :||:|:::.:|.:||||.         |.::.....||  |..:|||:.|:   :|:..
Zfish   501 W-----NGMIGEVFYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTV---SPSAF 557

  Fly   371 PSWRTNIMPFNNRAWLVL-ISTLVICGTFLYFMKYVSYRLRYSGTQVKFHHSRK--------LEK 426
                  :.|::...|::: :..|.:....::..:|.| .:.|:.:.|    |.|        :.|
Zfish   558 ------LEPYSPAVWVMMFVMCLTVVAVTVFVFEYCS-PVGYNRSLV----SAKDPGGPTFTIGK 611

  Fly   427 SMLDIFALF------IQQPSAPLSFDRFAPRFFLATILCATITLENIYSGQLKSMLTFPFYSAPV 485
            |:..::.:.      |:.|....|........|.|.|..|:.|         .::..|......:
Zfish   612 SVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYT---------ANLAAFMIQEQYI 667

  Fly   486 DTIEKWAQSGWKWSAPSIIW----VHTVQSSDLETEQILARNF-EVHDYSYLSNVSFMPNYGFGI 545
            ||:.  ..|..|:..|...:    ..||.:.  .||:.:..|: |:|.:....|..       |:
Zfish   668 DTVS--GLSDKKFQKPQDQYPPFRFGTVPNG--STERNIRSNYPEMHSHMVKYNQK-------GV 721

  Fly   546 E----RLSSGSLSVGDYVSTEALENRIVLHDDLYFDYTRAVSIRGWILMPELNKHIRTCQETGLY 606
            |    .|.:|.|..  ::...|:.|.:...|    :..:.|:|....:.......|...:|:
Zfish   722 EDALNSLKTGKLDA--FIYDAAVLNYMAGKD----EGCKLVTIGSGKVFATTGYGIALQKES--- 777

  Fly   607 FHWE-------LEFIDKYMDKKKQEV-LMDLANGHKVKGAPQALDVRNIAGALFVLAFGVAFAGC 663
             .|:       |:|:.....:|.|.| |..:....|.:.....||:.|:||..::|...:..:..
Zfish   778 -RWKRPIDLALLQFLADGDTQKLQTVWLTGICRNEKKEVMSSKLDIDNMAGVFYMLLVAMGLSLL 841

  Fly   664 ALVAELLIH 672
            ....|.|::
Zfish   842 VFAWEHLLY 850

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir92a	NP_001097845.2	None
grin2ca	NP_001352716.1	PBP1_iGluR_NMDA_NR2	38..393	CDD:380601	4/11 (36%)
		PBP2_iGluR_NMDA_Nr2	409..810	CDD:270436	88/450 (20%)
		NMDAR2_C	847..>938	CDD:463148	1/4 (25%)