Protein Alignment Sirt2 and cobB

DIOPT Version :10

• Sequence 1: NP_650880.3
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_415638.3
• Gene: cobB / 945687
• ECOCYCID: G6577
• Length: 279
• Species: Escherichia coli
• Alignment Length: 262
• Identity: 70/262 - (26%)
• Similarity: 105/262 - (40%)
• Gaps: 53/262 - (20%)

  Fly    58 EKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFD 122
            :||:|:.     .|..||      :.:.|||||..:||..||: ..||:...:..::..|
E. coli    31 DKVVPEA-----MEKPRV------LVLTGAGISAESGIRTFRA-ADGLWEEHRVEDVATP----- 78

  Fly   123 LDYFEKNP----APFFALAKELYPGSFIPTPAHYFIR----LLNDKGLLQRHYTQNIDTLDRLTG 179
             :.|:::|    |.:.|..::|......|..||..:.    .|.|:.||   .|||||.|....|
E. coli    79 -EGFDRDPELVQAFYNARRRQLQQPEIQPNAAHLALAKLQDALGDRFLL---VTQNIDNLHERAG 139

  Fly   180 LPEDKIIEAHGSFHTNHCIKCRKEYDMDWMKAEIFADRLP--KCQKCQ--GVVKPDIVFFGENLP 240
              ...:|..||......|.:..:.  :||.     .|..|  ||..||  ..::|.:|:||| :|
E. coli   140 --NTNVIHMHGELLKVRCSQSGQV--LDWT-----GDVTPEDKCHCCQFPAPLRPHVVWFGE-MP 194

  Fly   241 ---KRFYSSPEEDFQDCDLLIIMGTSLEVQPFASLVWRP---GPRCIRLLINRDAVGQASCVLFM 299
               ...|.:    ....|:.|.:|||..|.|.|..|...   |...:.|.:....||......:.
E. coli   195 LGMDEIYMA----LSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYY 255

  Fly   300 DP 301
            .|
E. coli   256 GP 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_650880.3	SIRT1	79..330	CDD:238699	64/241 (27%)
cobB	NP_415638.3	PRK00481	31..271	CDD:234777	70/262 (27%)