Protein Alignment Sirt2 and HST4

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_010477.3
• Gene: HST4 / 851772
• SGDID: S000002599
• Length: 370
• Species: Saccharomyces cerevisiae
• Alignment Length: 397
• Identity: 98/397 - (24%)
• Similarity: 142/397 - (35%)
• Gaps: 129/397 - (32%)

  Fly    13 TTPSNSSSSDDDEEAPDDTMDKVRRFFANTLHLGGSSDAKEEVKVEKVIPDLSF----------D 67
            |.||.:......|...::.: |.||..         ...|:.|:..|  |.||:          |
Yeast    10 TPPSTAEKKPQTENRCNENL-KPRRLL---------PQLKKSVRNRK--PRLSYRPELNSVFDLD 62

  Fly    68 GFAE----------HW-RVHGF--------RKIVTMVGAGISTSAGIPDFRSPGSGLYS------ 107
            .:.:          |. |..||        :::|.:.|||||.:|||||||| ..|::|
Yeast    63 AYVDSTHLSKSQRHHMDRDAGFISYALNYSKRMVVVSGAGISVAAGIPDFRS-SEGIFSTVNGGS 126

  Fly   108 --NLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQN 170
              :|..|...:......|. |.:.....|.|:|...|..|     |..:......|.|.|.||||
Yeast   127 GKDLFDYNRVYGDESMSLK-FNQLMVSLFRLSKNCQPTKF-----HEMLNEFARDGRLLRLYTQN 185

  Fly   171 IDTLDRLTGLPE-----------DKIIEAHGSFHTNHCIKCR--KEYDMDWMKAEIFADR----L 218
            ||.||  |.||.           ...::.|||.....|.||.  |.:|.:..|.:...|.    :
Yeast   186 IDGLD--TQLPHLSTNVPLAKPIPSTVQLHGSIKHMECNKCLNIKPFDPELFKCDDKFDSRTEII 248

  Fly   219 PKCQKCQ----------------GVVKPDIVFFGENLPKRFYSSPEEDF----------QDCDLL 257
            |.|.:|:                |.::|.::.:.|       ..||.||          :..|.|
Yeast   249 PSCPQCEEYETVRKMAGLRSTGVGKLRPRVILYNE-------VHPEGDFIGEIANNDLKKRIDCL 306

  Fly   258 IIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVGQASCVLFMDPNTRSLLFDKPNNTR------D 316
            ||:||||::         ||.:.|..............||:::.:.      .|.|..      |
Yeast   307 IIVGTSLKI---------PGVKNICRQFAAKVHANRGIVLYLNTSM------PPKNVLDSLKFVD 356

  Fly   317 VAFLGDC 323
            :..||||
Yeast   357 LVVLGDC 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	80/302 (26%)
HST4	NP_010477.3	SIR2	77..370	CDD:223915	84/318 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000643
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910