Protein Alignment Sirt2 and sirt7

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: XP_001336438.3
• Gene: sirt7 / 796135
• ZFINID: ZDB-GENE-050208-612
• Length: 405
• Species: Danio rerio
• Alignment Length: 441
• Identity: 110/441 - (24%)
• Similarity: 168/441 - (38%)
• Gaps: 120/441 - (27%)

  Fly     6 VKKEEQPTTPSNSS-------SSDDDEE-----APDDTMDKVRRFFANTLHLGGSSDAKEEVKVE 58
            :::|:|..|....|       |...:||     |..||:.::.| ..|..||       .:.|.|
Zfish    24 IQREKQRQTMKTISKILQKCESEWTEEERSMLQAHQDTVQELSR-RQNRRHL-------LKRKQE 80

  Fly    59 KVIPDLSFDGFAEHWR---------VHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYEL 114
            :|..|      ||:.:         |...:.:|...||||||:|.|||:|.| :|:::.|:|
Zfish    81 EVFDD------AENLKTKVKQLAEAVQRAKHLVIYTGAGISTAASIPDYRGP-NGVWTQLQK--- 135

  Fly   115 PHPTAIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTG 179
            ....:..||...|                   ||..|..|.:|:...::|...:||.|.|...:|
Zfish   136 GRSVSTSDLSQAE-------------------PTLTHMSIWMLHKMKMVQHVVSQNCDGLHLRSG 181

  Fly   180 LPEDKIIEAHGSFHTNHCIKCRKEYDMDWMKAEIFADRLP--------KCQKCQGVVKPDIVFFG 236
            ||...:.|.||:.....|..|..  ..::::.....:|..        .|..|:..::..||.||
Zfish   182 LPRHALSELHGNMFIEVCDSCSP--PREFIRLFDVTERTALHRHGTGRSCPHCRAELRDTIVHFG 244

  Fly   237 E--NLPKRF-YSSPEEDFQDCDLLIIMGTSLEVQPFASLVW---RPGPRCIRLLINRDAVGQASC 295
            |  .|.:.. :....|..|..||::.:|:||:|....|.:|   ||..:..:|.|
Zfish   245 ERGTLEQPLNWKGAAEAAQRADLILCLGSSLKVLKKYSCLWCMNRPASKRPKLYI---------- 299

  Fly   296 VLFMDPNTRSLLFDKPNNTRDVAFLGDCDAGVMA-----LAKALGWDQELQQLITSERKKLSGSQ 355
                    .:|.:...:|...:...|.||| |||     ||.|:.....||..|.|..|.||..:
Zfish   300 --------VNLQWTPKDNLATLKIHGKCDA-VMALLMEELALAVPVYSRLQDPIFSMAKPLSPQE 355

  Fly   356 NS-------------EELQQGKEKPQSDPDKMTSG--------DRDKKDAS 385
            ..             ||:.| ...||.:...:..|        .|.||.:|
Zfish   356 QKSHSRKEIAPPSALEEVSQ-SAPPQGEGPAVQGGWFGRGYSKGRRKKKSS 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	69/269 (26%)
sirt7	XP_001336438.3	SIRT7	104..318	CDD:238701	62/256 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910