Protein Alignment Sirt2 and Sirt4

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: XP_036021467.1
• Gene: Sirt4 / 75387
• MGIID: 1922637
• Length: 393
• Species: Mus musculus
• Alignment Length: 351
• Identity: 86/351 - (24%)
• Similarity: 139/351 - (39%)
• Gaps: 114/351 - (32%)

  Fly    79 RKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYPG 143
            :|::.|.||||||.:||||:||...|||:...:..:.|      :|:....|     :.:..:..
Mouse    93 KKLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQH------IDFVRSAP-----VRQRYWAR 146

  Fly   144 SFI---------PTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIK 199
            :|:         |.|||:.:......|.|....|||:|.|....|  ..::.|.||..|...|:.
Mouse   147 NFVGWPQFSSHQPNPAHWALSNWERLGKLHWLVTQNVDALHSKAG--SQRLTELHGCMHRVLCLN 209

  Fly   200 CRKEY---------------------------DMDWMKAEIFADRLPKCQKCQGVVKPDIVFFGE 237
            |.::.                           |:...:.::.:.::|.|.:|.|.:|||:||||:
Mouse   210 CGEQTARRVLQERFQALNPSWSAEAQGVAPDGDVFLTEEQVRSFQVPCCDRCGGPLKPDVVFFGD 274

  Fly   238 NLPKRFYSSPEE-DF-----QDCDLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVGQASCV 296
            .:      :|:: ||     ::.|.|:::|:||:|           |..:|:           .|
Mouse   275 TV------NPDKVDFVHRRVKEADSLLVVGSSLQV-----------PDSVRV-----------AV 311

  Fly   297 LFMDPN-----------TRSLLFDKPNNTRDVAFLG-DCDAGVMALAKALGWDQELQQLITSERK 349
            .|..|.           ..::|...|..:.|:|.|. |...|            ||..|| ..|:
Mouse   312 AFAHPTGFILTAREQKLPIAILNIGPTRSDDLACLKLDSRCG------------ELLPLI-DPRR 363

  Fly   350 KLSGSQNSE------ELQQGKEKPQS 369
            :.|..|..|      ...|||||..|
Mouse   364 QHSDVQRLEMNFPLSSAAQGKEKALS 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	72/304 (24%)
Sirt4	XP_036021467.1	SIRT4	85..356	CDD:238700	73/315 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910