Protein Alignment Sirt2 and Sirt3

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_001171275.1
• Gene: Sirt3 / 64384
• MGIID: 1927665
• Length: 334
• Species: Mus musculus
• Alignment Length: 311
• Identity: 159/311 - (51%)
• Similarity: 194/311 - (62%)
• Gaps: 33/311 - (10%)

  Fly    46 GGSSDAKEEVKVEKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLK 110
            ||||:.|           .|....||..|.....::|.||||||||.:||||||||||||||||:
Mouse    51 GGSSEKK-----------FSLQDVAELLRTRACSRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQ 104

  Fly   111 KYELPHPTAIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLD 175
            :|::|:|.|||:|.:|..||.|||.||||||||.:.|...|||:|||:||.||.|.||||||.|:
Mouse   105 QYDIPYPEAIFELGFFFHNPKPFFMLAKELYPGHYRPNVTHYFLRLLHDKELLLRLYTQNIDGLE 169

  Fly   176 RLTGLPEDKIIEAHGSFHTNHCIKCRKEYDMDWMKAEIFADRLPKCQKCQGVVKPDIVFFGENLP 240
            |.:|:|..|::||||:|.|..|..||:.:..:.:.|::.|||:|:|..|.||||||||||||.||
Mouse   170 RASGIPASKLVEAHGTFVTATCTVCRRSFPGEDIWADVMADRVPRCPVCTGVVKPDIVFFGEQLP 234

  Fly   241 KRFYSSPEEDFQDCDLLIIMGTSLEVQPFASL---VWRPGPRCIRLLINRDAVGQASCVLFMDPN 302
            .||... ..||...|||:|:||||||:|||||   |.:..|   |||||||.||.    ..:.|
Mouse   235 ARFLLH-MADFALADLLLILGTSLEVEPFASLSEAVQKSVP---RLLINRDLVGP----FVLSP- 290

  Fly   303 TRSLLFDKPNNTRDVAFLGDCDAGVMALAKALGWDQELQQLITSERKKLSG 353
                      ..:||..|||...||..|...|||.|||..|:..||.||.|
Mouse   291 ----------RRKDVVQLGDVVHGVERLVDLLGWTQELLDLMQRERGKLDG 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	137/253 (54%)
Sirt3	NP_001171275.1	SIRT1	74..308	CDD:238699	137/252 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54280
OrthoDB	1	1.010	-	-		D512963at33208
OrthoFinder	1	1.000	-	-		FOG0000643
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101879
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R577
SonicParanoid	1	1.000	-	-		X1602
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.860