Protein Alignment Sirt2 and sirt6

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_001002071.1
• Gene: sirt6 / 415161
• ZFINID: ZDB-GENE-031007-2
• Length: 354
• Species: Danio rerio
• Alignment Length: 371
• Identity: 88/371 - (23%)
• Similarity: 148/371 - (39%)
• Gaps: 105/371 - (28%)

  Fly    50 DAKEEVKVEKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYEL 114
            |:.||:|.:  :..|:      .| :...:.:|...|||||||.||||||.| :|:::..::.|.
Zfish    25 DSPEELKTK--VETLA------QW-IRESQYMVVHSGAGISTSTGIPDFRGP-NGVWTMEERGET 79

  Fly   115 PHPTAIFDLDYFEKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTG 179
            ||....|:                     ...|:..|..:..:...|.|:...:||:|.|...:|
Zfish    80 PHFNTTFE---------------------DARPSLTHMALLQMQRTGHLKYLISQNVDGLHVRSG 123

  Fly   180 LPEDKIIEAHGSFHTNHCIKCRKEYDMDWMKAEI-------FAD--RLPKCQKCQGVVKPDIVFF 235
            .|.|::.|.||:.....|.||.|:|..|.:...:       :.|  |....:.|:|.:...|:.:
Zfish   124 FPRDRLSELHGNMFVEECEKCGKQYVRDTVVGVMGLKPTGRYCDVMRSRGLRSCRGKLISSILDW 188

  Fly   236 GENLPKRFYSSPEEDFQDCDLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVGQASCVLFMD 300
            .::||.|..:..:|..:..||.:.:||||:::|...|         .||..|  .|....::.:.
Zfish   189 EDSLPDRDLNRADEASRRADLALTLGTSLQIKPSGDL---------PLLTKR--TGGKLVIVNLQ 242

  Fly   301 PNTRSLLFDKPNNTRDVAFLGDCDAGVMA-LAKALGWD--------------------------- 337
            |...    ||..:.|...::.|    ||. |.|.||.|
Zfish   243 PTKH----DKHAHLRIYGYVDD----VMGQLMKLLGLDVPEWAGPTLCEDSGGDLDILPYGAWKK 299

  Fly   338 --------QELQQLITSERKK---------LSGSQNSEEL-QQGKE 365
                    :|....::.:||:         .:|.:..||: ::|||
Zfish   300 EVKIELKIEESNHTVSKKRKRKEQHAEEGYKNGVKVEEEMKEEGKE 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	68/260 (26%)
sirt6	NP_001002071.1	SIRT7	46..257	CDD:238701	65/247 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54280
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920