Protein Alignment Sirt2 and Sirt5

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_001004256.1
• Gene: Sirt5 / 306840
• RGDID: 1303285
• Length: 310
• Species: Rattus norvegicus
• Alignment Length: 269
• Identity: 71/269 - (26%)
• Similarity: 104/269 - (38%)
• Gaps: 72/269 - (26%)

  Fly    28 PDDTMDKVRRFFANTLHLGGSSDAKEEVKVEKVIPDLSFDGFAEHWRVHGFRKIVTMVGAGISTS 92
            |...|...|:.|||..|                                    ||.:.|||:|..
  Rat    36 PSSNMADFRKCFANAKH------------------------------------IVIISGAGVSAE 64

  Fly    93 AGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPA---PFFALAKELYPGSFIPTPAHYFI 154
            :|:|.||..| |.:...:...|..|.|      |..||:   .|:...:|:.... .|.|.|..|
  Rat    65 SGVPTFRGTG-GYWRKWQAQHLATPLA------FAHNPSQVWEFYHYRREVMRNK-EPNPGHLAI 121

  Fly   155 ----RLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIKC---RKEY-------- 204
                ..|.|:|......|||||.|.|..|  ...::|.||:.....|..|   .:.|
  Rat   122 AQCEARLRDQGRRVVVITQNIDELHRKAG--TKNLLEIHGTLFKTRCTSCGNVAENYKSPICPAL 184

  Fly   205 ------DMDWMKAEIFADRLPKCQK--CQGVVKPDIVFFGENLPKRFYSSPEEDFQDCDLLIIMG 261
                  :.|..::.|...:||:|::  |.|:::|.:|:|||||........:.:...|||.:::|
  Rat   185 LGKGAPEPDTQESRIPVHKLPRCEEAGCGGLLRPHVVWFGENLDPAILKEVDRELARCDLCLVVG 249

  Fly   262 TSLEVQPFA 270
            ||..|.|.|
  Rat   250 TSSVVYPAA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	64/218 (29%)
Sirt5	NP_001004256.1	SIRT5_Af1_CobB	51..301	CDD:238703	65/254 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54280
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920