Protein Alignment Sirt2 and Sirt4

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: NP_001100617.2
• Gene: Sirt4 / 304539
• RGDID: 1310413
• Length: 319
• Species: Rattus norvegicus
• Alignment Length: 230
• Identity: 61/230 - (26%)
• Similarity: 105/230 - (45%)
• Gaps: 61/230 - (26%)

  Fly    79 RKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAPFFALAKELYPG 143
            :|::.|.||||||.:||||:||...|||:...:..:.|      :|:....|     :.:..:..
  Rat    60 KKLLVMTGAGISTESGIPDYRSEKVGLYARTDRRPIQH------IDFIRSAP-----VRQRYWAR 113

  Fly   144 SFI---------PTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHCIK 199
            :|:         |.|||:.:......|.|....|||:|.|....|  ..::.|.||..|...|:.
  Rat   114 NFVGWPQFSSHQPNPAHWALSNWEKLGKLHWLVTQNVDALHSKAG--NQRLTELHGCMHRVLCLS 176

  Fly   200 CRKEY---------------------------DMDWMKAEIFADRLPKCQKCQGVVKPDIVFFGE 237
            |.::.                           |:...:.::.:.|:|.|.:|.|.:|||:||||:
  Rat   177 CGEQTARRVLQDRFQALNPSWSAEAQGVAPDGDVFLTEEQVRSFRVPCCDRCGGPLKPDVVFFGD 241

  Fly   238 NLPKRFYSSPEE-DF-----QDCDLLIIMGTSLEV 266
            .:      :|:: ||     ::.|.|:::|:||:|
  Rat   242 TV------NPDKVDFVHQRVKEADSLLVVGSSLQV 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	61/230 (27%)
Sirt4	NP_001100617.2	SIRT4	52..313	CDD:238700	61/230 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910