| Sequence 1: | NP_001287422.2 | Gene: | Sirt2 / 42414 | FlyBaseID: | FBgn0038788 | Length: | 386 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_036369.2 | Gene: | SIRT2 / 22933 | HGNCID: | 10886 | Length: | 389 | Species: | Homo sapiens |
| Alignment Length: | 399 | Identity: | 183/399 - (45%) |
|---|---|---|---|
| Similarity: | 251/399 - (62%) | Gaps: | 40/399 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 9 EEQPTTP--------SNSSSSDDDEE----APDDTMDKVRRFFANTLHLGGSSDAKEEVKVEKVI 61
Fly 62 PDLSFDGFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYF 126
Fly 127 EKNPAPFFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGS 191
Fly 192 FHTNHCI--KCRKEYDMDWMKAEIFADRLPKCQKCQGVVKPDIVFFGENLPKRFYSSPEEDFQDC 254
Fly 255 DLLIIMGTSLEVQPFASLVWRPGPRCIRLLINRDAVGQASCVLFMDPNTRSLL-------FDKPN 312
Fly 313 NTRDVAFLGDCDAGVMALAKALGWDQELQQLITSERKKL-----SGSQNSEELQQGKEKPQSDPD 372
Fly 373 KMTSGDRDK 381 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Sirt2 | NP_001287422.2 | SIRT1 | 79..330 | CDD:238699 | 147/259 (57%) |
| SIRT2 | NP_036369.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..34 | 7/30 (23%) | |
| Nuclear export signal | 41..51 | 4/9 (44%) | |||
| SIRT1 | 77..331 | CDD:238699 | 147/259 (57%) | ||
| Peptide inhibitor binding | 116..120 | 2/3 (67%) | |||
| Peptide inhibitor binding | 232..301 | 37/74 (50%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 351..389 | 7/37 (19%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 266 | 1.000 | Domainoid score | I1898 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H40823 | |
| Inparanoid | 1 | 1.050 | 349 | 1.000 | Inparanoid score | I2293 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG54280 | |
| OrthoDB | 1 | 1.010 | - | - | D512963at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000643 | |
| OrthoInspector | 1 | 1.000 | - | - | oto88785 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101879 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR48252 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X1602 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 12 | 11.980 | |||||