Protein Alignment Sirt2 and sirt2

DIOPT Version :9

• Sequence 1: NP_001287422.2
• Gene: Sirt2 / 42414
• FlyBaseID: FBgn0038788
• Length: 386
• Species: Drosophila melanogaster
• Sequence 2: XP_002935827.4
• Gene: sirt2 / 100489469
• XenbaseID: XB-GENE-987375
• Length: 397
• Species: Xenopus tropicalis
• Alignment Length: 382
• Identity: 185/382 - (48%)
• Similarity: 249/382 - (65%)
• Gaps: 17/382 - (4%)

  Fly     3 DIEVKKEEQPTTPSNSSSSDDDEEAPDDTMDKVRRFFANTLHLGGSSDAKEEVKVEKVIPDLSFD 67
            |:..:.|:.    .:|.||:|...|.:  ||.:|..|:.||.:|         ..|||:.:||.:
 Frog    28 DLTAQAEDS----EDSDSSEDISGASE--MDYLRNLFSRTLGIG---------TPEKVLDELSIE 77

  Fly    68 GFAEHWRVHGFRKIVTMVGAGISTSAGIPDFRSPGSGLYSNLKKYELPHPTAIFDLDYFEKNPAP 132
            |.:........:.:|.||||||||||||||||||||||||||:||.||:|.|||.:.||::||.|
 Frog    78 GISRFMLSEKCKNVVCMVGAGISTSAGIPDFRSPGSGLYSNLQKYNLPYPEAIFQIGYFKENPEP 142

  Fly   133 FFALAKELYPGSFIPTPAHYFIRLLNDKGLLQRHYTQNIDTLDRLTGLPEDKIIEAHGSFHTNHC 197
            |||||:||:||.|.||..|||||||.:||||.|.|:||||||:|:.||..|.::||||:||::||
 Frog   143 FFALARELFPGQFKPTICHYFIRLLKEKGLLLRCYSQNIDTLERVAGLTSDDLVEAHGTFHSSHC 207

  Fly   198 IK--CRKEYDMDWMKAEIFADRLPKCQKCQGVVKPDIVFFGENLPKRFYSSPEEDFQDCDLLIIM 260
            :.  ||.||.:.|||.:||:|.:|||:||..:||||||||||:||.||:|:.:.||...||||:|
 Frog   208 VDTFCRAEYSLSWMKEKIFSDLIPKCEKCNNLVKPDIVFFGESLPSRFFSAIKSDFPKVDLLIVM 272

  Fly   261 GTSLEVQPFASLVWRPGPRCIRLLINRDAVGQASCVLFMDPNTRSLLFDKPNNTRDVAFLGDCDA 325
            ||||:||||||||.:...:..|||||::..||......:......:.||.....||||:|||||.
 Frog   273 GTSLQVQPFASLVSKVSSKTPRLLINKELAGQGDPFFSVFGFGGGMDFDSEKAYRDVAWLGDCDD 337

  Fly   326 GVMALAKALGWDQELQQLITSERKKLSGSQNSEELQQGKEKPQSDPDKMTSGDRDKK 382
            |.:|||..|||..||::|:..|...:..:..:.:.::.|....|..:...:...|:|
 Frog   338 GCLALADFLGWKAELEELVKKEHAAIDAAAEAAKKKESKPGGSSSEESSAANASDEK 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sirt2	NP_001287422.2	SIRT1	79..330	CDD:238699	151/252 (60%)
sirt2	XP_002935827.4	SIRT1	89..342	CDD:238699	151/252 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	272	1.000	Domainoid score	I1780
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H40823
Inparanoid	1	1.050	356	1.000	Inparanoid score	I2180
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D512963at33208
OrthoFinder	1	1.000	-	-		FOG0000643
OrthoInspector	1	1.000	-	-		oto102657
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R577
SonicParanoid	1	1.000	-	-		X1602
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090