DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4360 and Bcl11a

DIOPT Version :9

Sequence 1:NP_650879.1 Gene:CG4360 / 42413 FlyBaseID:FBgn0038787 Length:556 Species:Drosophila melanogaster
Sequence 2:NP_001178612.1 Gene:Bcl11a / 305589 RGDID:1309923 Length:835 Species:Rattus norvegicus


Alignment Length:557 Identity:119/557 - (21%)
Similarity:191/557 - (34%) Gaps:164/557 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    84 QAMLHPQHPLVHLLDISTTTANSGGGGGGSHTPI--SPMKQEVQSVISEEEVVVDDPRKKKQCHV 146
            |.:|.|..|                   ||..|.  :|....:||.....:    .|.|.|.|..
  Rat   340 QRLLQPFQP-------------------GSKPPFLATPPLPPLQSAPPPSQ----PPVKSKSCEF 381

  Fly   147 CKNKFRQLTTLRNHMKIHTDERPYKCKHCDKAFRQISTLTNHVKIH------------------T 193
            |...|:..:.|..|.:.||.|:||||..||.|..|.|.|..|:|.|                  :
  Rat   382 CGKTFKFQSNLVVHRRSHTGEKPYKCNLCDHACTQASKLKRHMKTHMHKSSPMTVKSDDGLSTAS 446

  Fly   194 GEKPFTCNICAKDFRQQSTLINHIKTHKAAESSTPTSLLNYQPQTGSGKHRKSQMHQAYQQQHQR 258
            ..:|.|.::.........:::...|:     .:.|    |..|:.|..:..:....:..:::.:.
  Rat   447 SPEPGTSDLVGSASSALKSVVAKFKS-----ENDP----NLIPENGDEEEEEDDEEEEEEEEEEE 502

  Fly   259 VQISKTL---YSGSYSSPAAEELVKPFQCSVC-----KRRFPQ------LSTLHN---------- 299
            .:::::.   |....|..||.......:.:|.     .|..|.      ||::.:          
  Rat   503 EELTESERVDYGFGLSLEAARHHENSSRGAVVGVGDEGRALPDVMQGMVLSSMQHFSEAFHQVLG 567

  Fly   300 --HERTHIDPKPYKCETCDKSFSQLATLANHKKIHTGDKPYTCSYCHMQFRQQSTLTNHLKTHTH 362
              |:|:|:.......:|||:                                     :.:...:.
  Rat   568 EKHKRSHLAEAEGHRDTCDE-------------------------------------DSVAGESD 595

  Fly   363 QIAPGGVGGAG-----GGGGAVTATVDHSMPAPLAPGTQQ--------LTSGLLPNN-------L 407
            :|..|.|.|.|     ...|.::..:....|:.|:|.:::        |....:||.       |
  Rat   596 RIDDGTVNGRGCSPGESASGGLSKKLLLGSPSSLSPFSKRIKLEKEFDLPPAAMPNTENVYSQWL 660

  Fly   408 HGSTANIIQLDHHPLLHFLD-------GSTTVSSVVATAAANTKVEHFQAG-----GSPSGRMTV 460
            .|..|:....|  |.|.|.|       .|:..||...:...:|.......|     |:.||    
  Rat   661 AGYAASRQLKD--PFLTFGDSRQSPFASSSEHSSENGSLRFSTPPGELDGGISGRSGTGSG---- 719

  Fly   461 VGTINMLKGDNPDRPFG--------CSVCQRFFSQQSTLVNHIKTHTGEKPYKCKICEVNFRQVA 517
             |:...:.|..|.||..        |..|.:.|...|.|..|.::||||:||||::|.....|.:
  Rat   720 -GSTPHISGPGPGRPSSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSS 783

  Fly   518 TLNNHMKIH--TGEKPYNCSFCPKQFRQKSTLQNHLR 552
            .|..|||.|  .|:..|.|..|...|...|||:.|::
  Rat   784 KLTRHMKTHGQVGKDVYKCEICKMPFSVYSTLEKHMK 820

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4360NP_650879.1 C2H2 Zn finger 144..164 CDD:275368 5/19 (26%)
zf-H2C2_2 157..181 CDD:290200 12/23 (52%)
C2H2 Zn finger 172..192 CDD:275368 9/19 (47%)
zf-H2C2_2 185..209 CDD:290200 6/41 (15%)
C2H2 Zn finger 200..220 CDD:275368 1/19 (5%)
C2H2 Zn finger 284..304 CDD:275368 7/42 (17%)
zf-C2H2_8 287..363 CDD:292531 10/98 (10%)
C2H2 Zn finger 312..332 CDD:275368 3/19 (16%)
C2H2 Zn finger 340..360 CDD:275368 0/19 (0%)
C2H2 Zn finger 478..498 CDD:275368 6/19 (32%)
zf-H2C2_2 491..515 CDD:290200 11/23 (48%)
C2H2 Zn finger 506..526 CDD:275368 7/19 (37%)
zf-H2C2_2 519..543 CDD:290200 10/25 (40%)
C2H2 Zn finger 534..554 CDD:275368 7/19 (37%)
Bcl11aNP_001178612.1 zf-C2H2 378..399 CDD:395048 5/20 (25%)
C2H2 Zn finger 379..399 CDD:275368 5/19 (26%)
zf-H2C2_2 391..416 CDD:404364 12/24 (50%)
C2H2 Zn finger 407..427 CDD:275368 9/19 (47%)
zf-C2H2 743..764 CDD:395048 6/20 (30%)
C2H2 Zn finger 744..764 CDD:275368 6/19 (32%)
zf-H2C2_2 756..781 CDD:404364 11/24 (46%)
C2H2 Zn finger 772..792 CDD:275368 7/19 (37%)
C2H2 Zn finger 802..820 CDD:275368 7/17 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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