DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4360 and Y111B2A.10

DIOPT Version :9

Sequence 1:	NP_650879.1	Gene:	CG4360 / 42413	FlyBaseID:	FBgn0038787	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_499640.1	Gene:	Y111B2A.10 / 176678	WormBaseID:	WBGene00013734	Length:	430	Species:	Caenorhabditis elegans

Alignment Length:	316	Identity:	72/316 - (22%)
Similarity:	122/316 - (38%)	Gaps:	83/316 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 QEVQSVIS--------EEEVVVDDPRKKKQ-------CHVCKNKFRQLTTLRNHMKIHTDE---- 167
            :|:||:|.        |::..::|...|..       |.:|...|.....|    :||||:
Worm   111 KELQSLIRMSQSQWKVEQKQQLEDSLLKPHTAGSIFTCVMCSKAFPNAEAL----QIHTDQVHDL 171

  Fly   168 --RPYKCKHCDKAFRQISTLTNHVKIHTGEKPFTCNICAKDFRQQSTLINHIKTHKAAES----- 225
              ..::||.|.||:::...|..|:.:|.  |...|:.|:..|:.:.:|.:||..|...::
Worm   172 SRLKHRCKLCGKAYKRKKNLDAHMALHL--KEIQCDNCSLVFQSEKSLQSHIIRHHQEDADELEV 234

  Fly   226 -STPTSLL-NYQPQTGSGKHRKSQMHQAYQQQHQRV----QISK--------------TLYSGSY 270
             ..|.|:. ...|.|      ..:.|:.|.:..:::    ::||              |:...|:
Worm   235 WKAPCSICKELFPST------SVKTHEWYCKNREKIIEKQRVSKILKVQSLPSSPALSTVSYASF 293

  Fly   271 SSPAAEELVKPF-----QCSVCKRRFPQLSTLHNH-ERTHIDPK------------------PYK 311
            ||.....:..|.     .|.||...|....::..| .|.|.|.|                  ||.
Worm   294 SSCQPGPITSPVSYRDKSCQVCGESFASRQSMLRHVGRKHPDAKNDPNVTAVRYISAESPKHPYA 358

  Fly   312 CETCDKSFSQLATLANHK-KIHTGDKPYTCSYCHMQFRQQSTLTNHLKTHTHQIAP 366
            |..|.|.|:.:..|:.|| ::|:....:.|:.||..:...|.|..|:|....:.||
Worm   359 CIECGKRFTTVTALSTHKARVHSQSNRFECTICHKSYPVPSELRKHIKRVHEKDAP 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4360	NP_650879.1	C2H2 Zn finger	144..164	CDD:275368	4/19 (21%)
		zf-H2C2_2	157..181	CDD:290200	10/29 (34%)
		C2H2 Zn finger	172..192	CDD:275368	7/19 (37%)
		zf-H2C2_2	185..209	CDD:290200	7/23 (30%)
		C2H2 Zn finger	200..220	CDD:275368	6/19 (32%)
		C2H2 Zn finger	284..304	CDD:275368	6/20 (30%)
		zf-C2H2_8	287..363	CDD:292531	24/95 (25%)
		C2H2 Zn finger	312..332	CDD:275368	7/20 (35%)
		C2H2 Zn finger	340..360	CDD:275368	7/19 (37%)
		C2H2 Zn finger	478..498	CDD:275368
		zf-H2C2_2	491..515	CDD:290200
		C2H2 Zn finger	506..526	CDD:275368
		zf-H2C2_2	519..543	CDD:290200
		C2H2 Zn finger	534..554	CDD:275368
Y111B2A.10	NP_499640.1	C2H2 Zn finger	148..169	CDD:275368	8/24 (33%)
		zf-C2H2_8	151..221	CDD:292531	20/75 (27%)
		C2H2 Zn finger	178..198	CDD:275368	7/19 (37%)
		C2H2 Zn finger	204..224	CDD:275368	6/19 (32%)
		C2H2 Zn finger	312..333	CDD:275368	6/20 (30%)
		C2H2 Zn finger	359..380	CDD:275368	7/20 (35%)
		C2H2 Zn finger	388..409	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000